The global burden of fungal disease poses a substantial threat to human, animal, and
environmental health, endangering both human and livestock populations and creating …

Invasive candidiasis (IC), due to the yeast pathogen Candida, is still a major cause of in-
hospital morbidity and mortality. The limited number of antifungal drug classes and the …

The objectives of this study were to assess Candida spp. distribution and antifungal
resistance of candidaemia across Europe. Isolates were collected as part of the third ECMM …

Iron homeostasis, which is pivotal to virulence, is regulated by the phosphatidylinositol 3-
kinase CgVps34 in the human fungal pathogen Candida glabrata. Here, we identify CgPil1 …

Abstract Knowledge of the epidemiology and clinical characteristics of fungemia in southern
China is limited. We conducted a six-year retrospective descriptive study to analyze the …

Mitochondrial dysfunction or morphological abnormalities in human pathogenic fungi are
known to contribute to azole resistance; however, the underlying molecular mechanisms are …

Objectives The applicability of a simple and high-throughput method for quantitative
characterization of biofilm formation by Candida boidinii was tested in order to evaluate the …

Methods A total of 236 Candida strains isolated from blood cultures in our hospital over a
four-year period were analyzed and their antifungal susceptibilities were studied …

With the widespread of HIV infection, increased organ transplants and chemo/radiotherapy,
and wide application of antifungal drugs, the worldwide trend of Candida infection has …

Conclusions: We report a case of recurrent asymptomatic candiduria caused by azole-
resistant Candida glabrata in a young healthy female with a novel CARD9 mutation. A …