Immune response following traumatic spinal cord injury: Pathophysiology and therapies

RC Sterner, RM Sterner - Frontiers in immunology, 2023 - frontiersin.org
Traumatic spinal cord injury (SCI) is a devastating condition that is often associated with
significant loss of function and/or permanent disability. The pathophysiology of SCI is …

Electrical stimulation for the treatment of spinal cord injuries: A review of the cellular and molecular mechanisms that drive functional improvements

RM Dorrian, CF Berryman, A Lauto… - Frontiers in Cellular …, 2023 - frontiersin.org
Spinal cord injury (SCI) is a devastating condition that causes severe loss of motor, sensory
and autonomic functions. Additionally, many individuals experience chronic neuropathic …

Schwann cell-derived exosomes and methylprednisolone composite patch for spinal cord injury repair

B Zhu, G Gu, J Ren, X Song, J Li, C Wang, W Zhang… - ACS …, 2023 - ACS Publications
Spinal cord injury (SCI) can cause permanent loss of sensory and motor function, and there
is no effective clinical treatment, to date. Due to the complex pathological process involved …

[HTML][HTML] Generation of direct current electrical fields as regenerative therapy for spinal cord injury: A review

L Matter, B Harland, B Raos, D Svirskis… - APL bioengineering, 2023 - pubs.aip.org
Electrical stimulation (ES) shows promise as a therapy to promote recovery and
regeneration after spinal cord injury. ES therapy establishes beneficial electric fields (EFs) …

The NF-κB pathway: a focus on inflammatory responses in spinal cord injury

Y Ding, Q Chen - Molecular Neurobiology, 2023 - Springer
Spinal cord injury (SCI) is a type of central nervous system trauma that can lead to severe
nerve injury. Inflammatory reaction after injury is an important pathological process leading …

Hydrogen promotes the effectiveness of bone mesenchymal stem cell transplantation in rats with spinal cord injury

S Luo, J Wu, Y Qiu, B Xiao, Y Xi, C Yang… - Stem Cells …, 2023 - Wiley Online Library
Although bone mesenchymal stem cell (BMSC) transplantation has been applied to the
treatment of spinal cord injury (SCI), the effect is unsatisfactory due to the specific …

Surgical management and denosumab for aneurysmal bone cysts of the spine in an Australian tertiary paediatric centre

JA Vanderniet, D Tsinas, CL Wall, CM Girgis… - Calcified Tissue …, 2023 - Springer
Aneurysmal bone cysts (ABC) are rare osteolytic, benign but often locally aggressive
tumours of the long bones or vertebrae. For spinal ABC, surgical management, embolisation …

Human adipose-derived stem cells reduce cellular damage after experimental spinal cord injury in rats

EN Vialle, L Fracaro, F Barchiki, AC Dominguez… - Biomedicines, 2023 - mdpi.com
Traumatic spinal cord injury (SCI) is a devastating condition without an effective therapy.
Cellular therapies are among the promising treatment strategies. Adult stem cells, such as …

Ca2+ Regulates Autophagy Through CaMKKβ/AMPK/mTOR Signaling Pathway in Mechanical Spinal cord Injury: An in vitro Study

FS Liu, C Jiang, Z Li, XB Wang, J Li, B Wang… - Neurochemical …, 2023 - Springer
Spinal cord injury (SCI), resulting in damage of the normal structure and function of the
spinal cord, would do great harm to patients, physically and psychologically. The …

Pediatric spinal cord injury with radiographic abnormality: the Beijing experience

Z Zou, S Kang, Y Hou, K Chen - The Spine Journal, 2023 - Elsevier
BACKGROUND CONTEXT Spinal cord injury (SCI) without radiographic abnormality
(SCIWORA) is a syndrome that usually occurs in children primarily because of the unique …