Developmental periods such as gestation and adolescence have enhanced plasticity
leaving the brain vulnerable to harmful effects from nicotine use. Proper brain maturation …

The main risk factor for chronic obstructive pulmonary disease (COPD) is active smoking.
However, a considerable amount of people with COPD never smoked, and increasing …

Importance Neighborhood segregation and poverty may be important drivers of health
inequities. Epigenomic factors, including DNA methylation clocks that may mark underlying …

Background Experimental studies suggest that exposures may impact respiratory health
across generations via epigenetic changes transmitted specifically through male germ cells …

Abstract Purpose of Review To summarize recent literature relating early-life environmental
exposures on DNA methylation in the placenta, to identify how variation in placental …

The accumulation of everyday exposures can impact health across the life course, but our
understanding of such exposures is impeded by our ability to delineate the relationship …

Background: The prenatal environment influences lifetime health; epigenetic mechanisms
likely predominate. In 2016, the first international consortium paper on cigarette smoking …

Epigenetics functions as a bridge between host genetic & environmental factors, aiding in
human health and diseases. Many immune-related diseases, including infectious and …

Background Genetic variants can modulate phenotypic outcomes via epigenetic
intermediates, for example at methylation quantitative trait loci (mQTL). We present the first …

Many different lifestyle factors and chemicals present in the environment are a threat to the
reproductive tracts of humans. The potential for parental preconception exposure to alter …