Cancer stem cells (CSCs) have drawn much attention as important tumour-initiating cells
that may also be crucial for recurrence after chemotherapy. Although the activity of CSCs in …

Cancer cell heterogeneity is a key contributor to therapeutic failure and post-treatment
recurrence. Targeting cell subpopulations responsible for chemoresistance and recurrence …

Background Management of clear cell renal cell carcinoma (ccRCC) has changed rapidly in
recent years with the advent of immune checkpoint inhibitors (ICIs). However, only a limited …

Recently, radioresistant cancer cells surviving radiotherapy have been suggested to show
more aggressive phenotypes than parental cells, and the underlying mechanisms may be …

Despite recent therapy advances and a better understanding of colon cancer biology, it
remains one of the major causes of death. The cancer stem cells, associated with the …

Leptocarpha rivularis is a native South American plant used ancestrally by Mapuche people
to treat gastrointestinal ailments. L. rivularis flower extracts are rich in molecules with …

The ability of cells to differentiate into various lineages is referred to as phenotypic plasticity.
Cells in embryonic development have phenotypic plasticity, which is strictly regulated in …

Cancer stem cells (CSCs), a small population of cells having properties of self-renewal,
differentiate into multiple cell lineages. Also, they have higher genomic instability in …

Das kutane Plattenepithelkarzinom (cSCC) macht 20% aller Hautkrebserkrankungen aus.
Aktinische Keratosen (AK) sind die Vorstufen von cSCC, und es gibt immer noch keine …