Demyelinating diseases alter myelin or the coating surrounding most nerve fibers in the
central and peripheral nervous systems. The grouping of human central nervous system …

Multiple sclerosis is a leading cause of neurological disability in adults. Heterogeneity in
multiple sclerosis clinical presentation has posed a major challenge for identifying genetic …

Background: Whether genetic factors influence the long-term course of multiple sclerosis
(MS) is unresolved. Objective: To determine the influence of HLA-DRB1* 1501 on long-term …

Background and Objectives HLA-DRB1* 15: 01 (DR15) and MERTK are 2 risk genes for
multiple sclerosis (MS). The variant rs7422195 is an expression quantitative trait locus for …

Background and Objectives The major histocompatibility complex (MHC) locus has a
predominant role in the genetic predisposition to multiple sclerosis (MS), with 32 …

Multiple sclerosis risk has a well-established polygenic component, yet the genetic
contribution to disease course and severity remains unclear and difficult to examine …

Autoimmune diseases of the central nervous system such as multiple sclerosis (MS) are only
partially represented in current experimental models and the development of humanized …

VG Jokubaitis journals. sagepub. com/home/ms j 315 onset and again at 1, 3, 5 and 15
years with consistent MRI protocols. Furthermore, the cohort was largely untreated; only 25 …

Background: Guillain-Barré Syndrome (GBS) and multiple sclerosis are autoimmune
diseases associated with an immune system attack response against peripheral and central …

Demyelinating diseases alter myelin or the coating surrounding most nerve fibers in the
central and peripheral nervous systems. The grouping of human central nervous system …