PPAR-γ signaling in nonalcoholic fatty liver disease: Pathogenesis and therapeutic targets

H Chen, H Tan, J Wan, Y Zeng, J Wang… - Pharmacology & …, 2023 - Elsevier
Non-alcoholic fatty liver disease (NAFLD), currently the leading cause of global chronic liver
disease, has emerged as a major public health problem, more efficient therapeutics of which …

[HTML][HTML] Unraveling Obesity: Transgenerational Inheritance, Treatment Side Effects, Flavonoids, Mechanisms, Microbiota, Redox Balance, and Bioavailability—A …

R Naomi, SH Teoh, S Halim, H Embong, Z Hasain… - Antioxidants, 2023 - mdpi.com
Obesity is known as a transgenerational vicious cycle and has become a global burden due
to its unavoidable complications. Modern approaches to obesity management often involve …

[HTML][HTML] The Antioxidant Properties of Lavandula multifida Extract Contribute to Its Beneficial Effects in High-Fat Diet-Induced Obesity in Mice

JA Molina-Tijeras, AJ Ruiz-Malagón, L Hidalgo-García… - Antioxidants, 2023 - mdpi.com
Obesity is a worldwide public health problem whose prevalence rate has increased steadily
over the last few years. Therefore, it is urgent to improve the management of obesity and its …

[HTML][HTML] Defining the lipid profiles of human milk, infant formula, and animal milk: implications for infant feeding

AD George, S Paul, T Wang, K Huynh, C Giles… - Frontiers in …, 2023 - frontiersin.org
Background Breastfed infants have lower disease risk compared to formula-fed infants,
however, the mechanisms behind this protection are unknown. Human milk has a complex …

[HTML][HTML] Experimental animal models of chronic inflammation

M Rafiyan, S Sadeghmousavi… - Current Research in …, 2023 - Elsevier
Inflammation is a general term for a wide variety of both physiological and
pathophysiological processes in the body which primarily prevents the body from diseases …

[HTML][HTML] Post-effects of time-restricted feeding against adipose tissue inflammation and insulin resistance in obese mice

N Yun, J Nah, MN Lee, D Wu, M Pae - Nutrients, 2023 - mdpi.com
Time-restricted feeding (TRF) has been shown to improve the disordered metabolic and
immunologic functions associated with obesity, however little is known about its post-effects …

[HTML][HTML] Assessing the in vitro and in vivo performance of L-carnitine-loaded nanoparticles in combating obesity

B Uner, AD Ergin, IA Ansari, MS Macit-Celebi… - Molecules, 2023 - mdpi.com
Addressing obesity is a critical health concern of the century, necessitating urgent attention.
L-carnitine (LC), an essential water-soluble compound, plays a pivotal role in lipid …

Acute effects of a single moderate-intensity exercise bout performed in fast or fed states on cell metabolism and signaling: comparison between lean and obese rats

ÉL Vogt, MC Von Dentz, DS Rocha, JFA Model… - Life Sciences, 2023 - Elsevier
Aims Although the benefits of exercise can be potentiated by fasting in healthy subjects, few
studies evaluated the effects of this intervention on the metabolism of obese subjects. This …

Adipose tissue in lymphedema: a central feature of pathology and target for pharmacologic therapy

JS Burton, AC Sletten, E Marsh, MD Wood… - … Research and Biology, 2023 - liebertpub.com
Lymphedema is a chronic condition of impaired lymphatic flow that results in limb swelling
and debilitation. The pathophysiology of lymphedema is characterized by lymphatic stasis …

Dietary n-3 and n-6 polyunsaturated fatty acids differentially modulate the adiponectin and leptinmediated major signaling pathways in visceral and subcutaneous …

P Sharma, C Bhandari, N Agnihotri - Nutrition Research, 2023 - Elsevier
Obesity is a chronic metabolic disease that involves excessive accumulation of fat in white
adipose tissue (WAT). Apart from storing excess fats, WAT also serves as an important …