[HTML][HTML] Immunomodulatory glycomedicine: Introducing next generation cancer glycovaccines
Cancer remains a leading cause of death worldwide due to the lack of safer and more
effective therapies. Cancer vaccines developed from neoantigens are an emerging strategy …
effective therapies. Cancer vaccines developed from neoantigens are an emerging strategy …
[HTML][HTML] DNGR-1-mediated cross-presentation of dead cell-associated antigens
Conventional dendritic cells type 1 (cDC1) are critical for inducing protective CD8+ T cell
responses to tumour and viral antigens. In many instances, cDC1 access those antigens in …
responses to tumour and viral antigens. In many instances, cDC1 access those antigens in …
IL-6 selectively suppresses cDC1 specification via C/EBPβ
Cytokines produced in association with tumors can impair antitumor immune responses by
reducing the abundance of type 1 conventional dendritic cells (cDC1), but the mechanism …
reducing the abundance of type 1 conventional dendritic cells (cDC1), but the mechanism …
XCR1 expression distinguishes human conventional dendritic cell type 1 with full effector functions from their immediate precursors
L Heger, L Hatscher, C Liang… - Proceedings of the …, 2023 - National Acad Sciences
Dendritic cells (DCs) are major regulators of innate and adaptive immune responses. DCs
can be classified into plasmacytoid DCs and conventional DCs (cDCs) type 1 and 2. Murine …
can be classified into plasmacytoid DCs and conventional DCs (cDCs) type 1 and 2. Murine …
Guidelines for mouse and human DC generation
MB Lutz, S Ali, C Audiger, SE Autenrieth… - European journal of …, 2023 - Wiley Online Library
This article is part of the Dendritic Cell Guidelines article series, which provides a collection
of state‐of‐the‐art protocols for the preparation, phenotype analysis by flow cytometry …
of state‐of‐the‐art protocols for the preparation, phenotype analysis by flow cytometry …
The Conventional Dendritic Cell 1 Subset Primes CD8+ T Cells and Traffics Tumor Antigen to Drive Antitumor Immunity in the Brain
JA Bowman-Kirigin, R Desai, BT Saunders… - Cancer immunology …, 2023 - AACR
The central nervous system (CNS) antigen-presenting cell (APC) that primes antitumor
CD8+ T-cell responses remains undefined. Elsewhere in the body, the conventional …
CD8+ T-cell responses remains undefined. Elsewhere in the body, the conventional …
Dendritic cell-targeting polymer nanoparticle-based immunotherapy for cancer: A review
Cancer immunity is dependent on dynamic interactions between T cells and dendritic cells
(DCs). Polymer-based nanoparticles target DC receptors to improve anticancer immune …
(DCs). Polymer-based nanoparticles target DC receptors to improve anticancer immune …
Dendritic Cell‐Mediated Cross‐Priming by a Bispecific Neutralizing Antibody Boosts Cytotoxic T Cell Responses and Protects Mice against SARS‐CoV‐2
R Lázaro‐Gorines, P Pérez, I Heras‐Murillo… - Advanced …, 2023 - Wiley Online Library
Administration of neutralizing antibodies (nAbs) has proved to be effective by providing
immediate protection against SARS‐CoV‐2. However, dual strategies combining virus …
immediate protection against SARS‐CoV‐2. However, dual strategies combining virus …
Enhanced in vitro type 1 conventional dendritic cell generation via the recruitment of hematopoietic stem cells and early progenitors by Kit ligand
In vitro culture of bone marrow (BM) with Fms‐like tyrosine kinase 3 ligand (Flt3L) is widely
used to study development and function of type 1 conventional dendritic cells (cDC1) …
used to study development and function of type 1 conventional dendritic cells (cDC1) …
Catching our breath: updates on the role of dendritic cell subsets in asthma
JD Lajiness, JM Cook‐Mills - Advanced biology, 2023 - Wiley Online Library
Dendritic cells (DCs), as potent antigen presenting cells, are known to play a central role in
the pathophysiology of asthma. The understanding of DC biology has evolved over the …
the pathophysiology of asthma. The understanding of DC biology has evolved over the …