Chiral separation has already become a crucial topic for effectively utilizing superfluous
racemates synthesized by chemical means and satisfying the growing requirements for …

The aqueous solubility of active pharmaceutical ingredients is one of the most important
features to be considered during the development of parenteral formulations in the …

In this study, the existing set of carbamazepine (CBZ) cocrystals was extended through the
successful combination of the drug with the positional isomers of acetamidobenzoic acid …

Pharmaceutical co-crystals represent a growing class of crystal forms in the context of
pharmaceutical science. They are attractive to pharmaceutical scientists because they …

Crystal structure prediction (CSP) is an invaluable tool in the pharmaceutical industry
because it allows to predict all the possible crystalline solid forms of small-molecule active …

Cocrystals have significant potential in various fields such as chemistry, material, and
medicine. For instance, pharmaceutical cocrystals have the ability to address issues …

In silico methods for predicting solvate formation can guide and simplify solid form screening
and solvent selection in crystallization processes. Solvates involve many complicated …

The pharmaceutical cocrystal landscape of ethenzamide has been addressed during the
past years with the aim of improving its physicochemical properties, mainly solubility and …

Various drugs are not able to reach the market due to their poor bioavailability and poor
solubility in aqueous media. Hence, several approaches are used to enhance the solubility …

The poor aqueous solubility of many modern active pharmaceutical ingredients (APIs) can
severely limit bioavailability. Cocrystals are emerging as a promising means of overcoming …