Metal-based photosensitizers as inducers of regulated cell death mechanisms

Y Zhang, BT Doan, G Gasser - Chemical Reviews, 2023 - ACS Publications
Over the last few decades, various forms of regulated cell death (RCD) have been
discovered and were found to improve cancer treatment. Although there are several reviews …

Mesenchymal stem cell-released oncolytic virus: an innovative strategy for cancer treatment

N Ghasemi Darestani, AI Gilmanova… - Cell Communication and …, 2023 - Springer
Oncolytic viruses (OVs) infect, multiply, and finally remove tumor cells selectively, causing no
damage to normal cells in the process. Because of their specific features, such as, the ability …

Chemotherapeutic and targeted drugs-induced immunogenic cell death in cancer models and antitumor therapy: An update review

J Zhai, X Gu, Y Liu, Y Hu, Y Jiang… - Frontiers in …, 2023 - frontiersin.org
As traditional strategies for cancer treatment, some chemotherapy agents, such as
doxorubicin, oxaliplatin, cyclophosphamide, bortezomib, and paclitaxel exert their anti-tumor …

Evoking Ferroptosis by Synergistic Enhancement of a Cyclopentadienyl Iridium‐Betulin Immune Agonist

M Lv, Y Zheng, J Wu, Z Shen, B Guo, G Hu… - Angewandte …, 2023 - Wiley Online Library
Ferroptosis is a form of programmed cell death driven by iron‐dependent lipid peroxidation
(LPO) with the potential for antitumor immunity activation. In this study, a nonferrous …

Mechanisms and applications of radiation-induced oxidative stress in regulating cancer immunotherapy

Z Zheng, J Su, X Bao, H Wang, C Bian, Q Zhao… - Frontiers in …, 2023 - frontiersin.org
Radiotherapy (RT) is an effective treatment option for cancer patients, which induces the
production of reactive oxygen species (ROS) and causes oxidative stress (OS), leading to …

NIR-II light evokes DNA cross-linking for chemotherapy and immunogenic cell death

Y Huang, D Wei, B Wang, D Tang, A Cheng, S Xiao… - Acta Biomaterialia, 2023 - Elsevier
As a DNA damaging agent, oxaliplatin (OXA) can induce immunogenic cell death (ICD) in
tumors to activate the immune system. However, the DNA damage induced by OXA is limited …

The crosstalk between ferroptosis and anti‐tumor immunity in the tumor microenvironment: molecular mechanisms and therapeutic controversy

Y Zheng, L Sun, J Guo, J Ma - Cancer Communications, 2023 - Wiley Online Library
The advent of immunotherapy has significantly reshaped the landscape of cancer treatment,
greatly enhancing therapeutic outcomes for multiple types of cancer. However, only a small …

Nanomedicine-mediated regulated cell death in cancer immunotherapy

Y Sun, T Lian, Q Huang, Y Chang, Y Li, X Guo… - Journal of Controlled …, 2023 - Elsevier
Immunotherapy has attracted widespread attention in cancer treatment and has achieved
considerable success in the clinical treatment of some tumors, but it has a low response rate …

Antibody–exatecan conjugates with a novel self-immolative moiety overcome resistance in colon and lung cancer

W Weng, T Meng, Q Zhao, Y Shen, G Fu, J Shi… - Cancer Discovery, 2023 - AACR
Antibody–drug conjugates (ADC) using DNA topoisomerase I inhibitor DXd/SN-38 have
transformed cancer treatment, yet more effective ADCs are needed for overcoming …

Multifunctional Nano‐Biomaterials for Cancer Therapy via Inducing Enhanced Immunogenic Cell Death

Q Chen, C Li, Q Wang - Small Methods, 2023 - Wiley Online Library
Immunotherapy is considered to be one of the most promising methods to overcome cancer.
Immunogenic cell death (ICD), as a special form of cell death that can trigger an antitumor …