The role of miR-128 in cancer development, prevention, drug resistance, and immunotherapy
A growing body of evidence has revealed that microRNA (miRNA) expression is
dysregulated in cancer, and they can act as either oncogenes or suppressors under certain …
dysregulated in cancer, and they can act as either oncogenes or suppressors under certain …
Dendritic cell-based immunotherapy: a potential player in oral cancer therapeutics
Background & aim: Dendritic cell (DC)-based immunotherapy modulates a patient's immune
system for recognition and subsequent removal of tumor cells. DC-mediated anticancer …
system for recognition and subsequent removal of tumor cells. DC-mediated anticancer …
Fibroblast mediated expansion and augmentation of immune regulatory cells for treatment of acute respiratory distress syndrome (ards)
T Ichim, P O'heeron - US Patent App. 17/906,883, 2023 - Google Patents
(201301); 461 K 35/33 (201301); 461K 35/51 (2013 01); A61P 29/00 (201801); A61P 11/00
(201801); 461 K 45/06 (201301); C12N 2502/1323 (2013 01)(57) ABSTRACT Embodiments …
(201801); 461 K 45/06 (201301); C12N 2502/1323 (2013 01)(57) ABSTRACT Embodiments …
Regenerative t regulatory cells
T Ichim, A Patel - US Patent App. 18/045,433, 2023 - Google Patents
Disclosed are T regulatory cells endogenously occurring or generated in vitro which
possess regenerative activity. In one embodiment said T regulatory cells are created by …
possess regenerative activity. In one embodiment said T regulatory cells are created by …
Generation of tumor immunity using astrocytes and astrocyte-dendritic cell combinations
J Veltmeyer - US Patent App. 18/191,791, 2023 - Google Patents
Disclosed are means, methods, and compositions of matter useful for treatment of
oncological indications through stimulation of protective anti-cancer immunity. In one …
oncological indications through stimulation of protective anti-cancer immunity. In one …
Suppression of diabetes using exosomes from stem cell programmed myeloid cells
T Ichim, A Patel - US Patent App. 17/931,868, 2023 - Google Patents
Described are antigen specific and antigen non-specific means of suppressing development
of Type 1 Diabetes in a mammal through administration of exosomes, microvesicles or …
of Type 1 Diabetes in a mammal through administration of exosomes, microvesicles or …
Chimeric antigen receptor regenerative gamma delta t cells
T Ichim, A Patel, T Warbington - US Patent App. 18/082,841, 2023 - Google Patents
Disclosed are novel method of inducing tissue regeneration through administration of
gamma delta T cells that have been endowed regenerative activity. In one embodiment said …
gamma delta T cells that have been endowed regenerative activity. In one embodiment said …
Therapeutic Monocytic Lineage Cells
T Ichim, A Patel - US Patent App. 17/865,881, 2023 - Google Patents
LOKCTEFSRHRXRJ-UHFFFAOYSA-I dipotassium trisodium dihydrogen phosphate
hydrogen phosphate dichloride Chemical compound P (= O)(O)(O)[O-].[K+]. P (= O)(O)([O …
hydrogen phosphate dichloride Chemical compound P (= O)(O)(O)[O-].[K+]. P (= O)(O)([O …
Increasing responses to checkpoint inhibitors by extracorporeal apheresis
TE Ichim, SF Josephs, SM Prince, A Jafri… - US Patent …, 2023 - Google Patents
The invention provides means, methods, and compositions of matter useful for enhancing
tumor response to checkpoint inhibitors. In one embodiment, the invention teaches …
tumor response to checkpoint inhibitors. In one embodiment, the invention teaches …