Structures and coordination chemistry of transporters involved in manganese and iron homeostasis

S Ray, R Gaudet - Biochemical Society Transactions, 2023 - portlandpress.com
A repertoire of transporters plays a crucial role in maintaining homeostasis of biologically
essential transition metals, manganese, and iron, thus ensuring cell viability. Elucidating the …

[HTML][HTML] Chaperone-assisted cryo-EM structure of P. aeruginosa PhuR reveals molecular basis for heme uptake

PP Knejski, SK Erramilli, AA Kossiakoff - bioRxiv, 2023 - ncbi.nlm.nih.gov
Pathogenic bacteria, such as Pseudomonas aeruginosa, depend on scavenging heme for
the acquisition of iron, an essential nutrient. The TonB-dependent transporter (TBDT) PhuR …