Syphilis: a modern resurgence

MS Ramchandani, CA Cannon… - Infectious Disease …, 2023 - id.theclinics.com
The rates of syphilis are rising in the United States and many high-income nations despite
the availability of screening and effective treatment. 1–4 The diagnosis of syphilis can be …

Advances in Diagnostics of Sexually Transmitted Infections

M Kahn, B Van Der Pol - Infectious Disease Clinics, 2023 - id.theclinics.com
Sexually transmitted infections (STIs) are caused by a variety of pathogens, many of which
have shared symptoms and all of which have shared transmission routes as implied by the …

Timely Diagnosis of Incubating Syphilis Infections Using Treponema pallidum Transcription-Mediated Amplification Assay

HCA Zondag, AP van Dam, J Bosch… - Clinical Infectious …, 2023 - academic.oup.com
Background Syphilis is a complex, multistage, sexually transmitted infection (STI) caused by
the bacterium Treponema pallidum subspecies pallidum (TP). New diagnostic tools are …

Refining timely diagnosis of early syphilis by using Treponema pallidum PCR or IgM immunoblotting next to conventional serology for syphilis

J Flipse, AM Niekamp, A Dirks… - Journal of Clinical …, 2023 - Am Soc Microbiol
Treponema pallidum subsp. pallidum is a fastidious spirochete and the etiologic agent of
syphilis, a sexually transmitted infection (STI). Syphilis diagnoses and disease staging are …

Treponema pallidum PCR screening at mucosal sites of asymptomatic men who have sex with men taking HIV pre-exposure prophylaxis

ET Aung, CK Fairley, DA Williamson… - Microbiology …, 2023 - Am Soc Microbiol
Early detection and treatment of syphilis will reduce the infectious period and transmission.
We aimed to determine whether screening men who have sex with men (MSM) taking HIV …

[HTML][HTML] Treponema pallidum Detection at Asymptomatic Oral, Anal, and Vaginal Sites in Adults Reporting Sexual Contact with Persons with Syphilis

ET Aung, CK Fairley, DA Williamson… - Emerging Infectious …, 2023 - ncbi.nlm.nih.gov
We investigated Treponema pallidum PCR positivity at mucosal sites (oral, anal, and vaginal
sites) among adults who had sexual contact with a person with syphilis (syphilis contacts) …

Specific detection of Treponema pallidum in clinical samples: validation of a qPCR assay combining two genomic targets

R Salle, C Mayslich, PA Grange, V Leducq… - Sexually Transmitted …, 2023 - sti.bmj.com
Objectives We evaluated a real-time quantitative PCR (qPCR) for detection of the
Treponema pallidum (TP) genome in clinical samples through simultaneous detection of two …

[PDF][PDF] Molecular Diagnostic Tools for Treponema pallidum

W Setyarini, N Wiqoyah… - Indonesian Journal of …, 2023 - pdfs.semanticscholar.org
Syphilis, a common sexually transmitted disease, is caused by Treponema pallidum subsp.
pallidum. Owing to the chameleonic behavior of syphilis, ocular involvement still presents a …

Developing a symptoms-based risk score for infectious syphilis among men who have sex with men

SA Nieuwenburg, E Hoornenborg… - Sexually transmitted …, 2023 - sti.bmj.com
Background Syphilis incidence is rising among men who have sex with men (MSM). An
online tool based on a risk score identifying men with higher risk of infectious syphilis could …

Prevalence of the related treponematoses syphilis and yaws and co-occurrence of pathogens causing similar skin lesions in Ghana

Y Agyekum Boaitey - 2023 - westminsterresearch.westminster.ac …
Yaws affects children in tropical regions while syphilis affects sexually active adults
worldwide. Despite various campaigns towards eradication of yaws and elimination of …