The emergence, implementation, and future growth of pharmacogenomics in psychiatry: a narrative review

CA Bousman, A Al Maruf, DF Marques… - Psychological …, 2023 - cambridge.org
Psychotropic medication efficacy and tolerability are critical treatment issues faced by
individuals with psychiatric disorders and their healthcare providers. For some people, it can …

[PDF][PDF] Nanotechnology as an efficient and effective alternative for wastewater treatment: an overview

H Pérez, OJ Quintero García… - Water Science & …, 2023 - iwaponline.com
The increase in the surface and groundwater contamination due to global population
growth, industrialization, proliferation of pathogens, emerging pollutants, heavy metals, and …

A multicenter double-blind, placebo-controlled trial of escitalopram in children and adolescents with generalized anxiety disorder

JR Strawn, L Moldauer, RD Hahn, A Wise… - Journal of Child and …, 2023 - liebertpub.com
Objective: Generalized anxiety disorder (GAD) in children and adolescents is associated
with substantial morbidity and increases the risk of future psychopathology. However …

[HTML][HTML] The pharmacogenetics of the new-generation antipsychotics–A scoping review focused on patients with severe psychiatric disorders

O Vasiliu - Frontiers in Psychiatry, 2023 - frontiersin.org
Exploring the possible correlations between gene variations and the clinical effects of the
new-generation antipsychotics is considered essential in the framework of personalized …

[HTML][HTML] Long-term effects of eliglustat on skeletal manifestations in clinical trials of patients with Gaucher disease type 1

TM Cox, J Charrow, E Lukina, PK Mistry, MC Foster… - Genetics in …, 2023 - Elsevier
Abstract Purpose Most patients with Gaucher disease have progressive and often disabling
skeletal manifestations. We examined the long-term effect of eliglustat treatment on bone …

[HTML][HTML] Global research trends and hotspots analysis of the scientific production of amitriptyline: a bibliometric approach

CS Pereira, JN Cruz, MKM Ferreira, DC Baia-da-Silva… - Pharmaceuticals, 2023 - mdpi.com
Amitriptyline was first introduced as a medication to treat depression. Over time, this
substance has been used to treat other conditions, such as gastrointestinal disorders …

[HTML][HTML] Implementation of pharmacogenetics in first-line care: evaluation of its use by general practitioners

D van der Drift, M Simoons, BCP Koch, G Brufau… - Genes, 2023 - mdpi.com
Pharmacogenetics (PGx) can explain/predict drug therapy outcomes. There is, however,
unclarity about the use and usefulness of PGx in primary care. In this study, we investigated …

The role of pharmacogenomics in precision psychiatry

M Manchia, MB Murri - Pharmacogenomics, 2023 - Taylor & Francis
The field of psychiatry is facing an important paradigm shift in the provision of clinical care
and mental health service organization toward personalization and integration of multimodal …

[HTML][HTML] Crocin lessens desipramine-induced phospholipidosis biomarker levels via targeting oxidative stress-related PI3K/Akt/mTOR signaling pathways in the rat …

AA El-Sheikh, HA Mahmoud, EA El-Kordy… - Acta Bio Medica …, 2023 - ncbi.nlm.nih.gov
Methods: Forty adult male rats were divided into 4 groups (n= 10): control group, a group
receiving intraperitoneal (IP) crocin (50 mg/kg/day), a group receiving IP desipramine (10 …

[HTML][HTML] Beyond the Asylum Walls: Tracing the Tapestry of Mental Health Interventions Across Eras and Cultures

P Gupta, KN Muneshwar, A Juganavar, T Shegekar - Cureus, 2023 - ncbi.nlm.nih.gov
This article offers an extensive review of the changing field of mental health therapies,
charting a transformational path from traditional methods to modern breakthroughs and …