Autophagy is the process by which cells degrade and recycle proteins and organelles to
maintain intracellular homeostasis. Generally, autophagy plays a protective role in cells, but …

Lysosomes are catabolic organelles that contribute to the degradation of intracellular
constituents through autophagy and of extracellular components through endocytosis …

Autophagy comprises a growing range of cellular pathways, which occupy central roles in
response to energy deprivation, organelle turnover and proteostasis. Over the years …

In addition to inhibiting persistent inflammation, phosphatase and tensin homolog deleted
from chromosome 10 (PTEN) is known as an important therapeutic target for alleviating …

The activation of stress response pathways in synovial fibroblasts (SF) is a hallmark of
rheumatoid arthritis (RA). CBP and p300 are two highly homologous histone acetyl …

Objectives Rheumatoid arthritis (RA) is a chronic systemic autoimmune disorder
characterized by progressive synovial inflammation and joint destruction, with a largely …

Lettuce (Lactuca sativa L.) contains various bioactive compounds that can reduce the
severity of inflammatory diseases. This study aimed to identify therapeutic effects and …

Rheumatoid arthritis (RA) is a chronic systemic autoimmune disease, characterized by
persistent joint inflammation, leading to cartilage and bone destruction. Autoantibody …

Background Rheumatoid arthritis (RA) is a chronic autoimmune disorder. Autophagy, a
regulator of cell homeostasis, can impact innate and adaptive immune cells activation and …

Background: Gingiva-derived mesenchymal stem cells (GMSCs) suppress immune and
inflammatory responses in experimental arthritis models. Here, we determined whether …