Acid catalyzed one-pot approach towards the synthesis of curcuminoid systems: unsymmetrical diarylidene cycloalkanones, exploration of their single crystals, optical …

A Ali, ZU Din, M Ibrahim, M Ashfaq, S Muhammad… - RSC …, 2023 - pubs.rsc.org
In the present study crystalline unsymmetrical diarylidene ketone derivatives BNTP and
BDBC have been prepared by two sequential acid catalyzed aldol condensation reactions in …

Diarylpentanoids, the privileged scaffolds in antimalarial and anti‐infectives drug discovery: A review

AH Ramli, SM Mohd Faudzi - Archiv der Pharmazie, 2023 - Wiley Online Library
Asia is a hotspot for infectious diseases, including malaria, dengue fever, tuberculosis, and
the pandemic COVID‐19. Emerging infectious diseases have taken a heavy toll on public …

Dibenzylideneacetone induces apoptosis in cervical cancer cells through Ros-mediated mitochondrial damage

AP Zani, CP Zani, ZU Din, E Rodrigues-Filho… - Antioxidants, 2023 - mdpi.com
Cervical cancer is a health problem among women worldwide. Considering the limitations of
prevention and antineoplastic chemotherapy against cervical cancer, research is needed to …

Structure-activity relationship of dibenzylideneacetone analogs against the neglected disease pathogen, Trypanosoma brucei

KR Francisco, L Monti, W Yang, H Park, LJ Liu… - Bioorganic & medicinal …, 2023 - Elsevier
Trypanosoma brucei is a protozoan parasite that causes Human African Trypanosomiasis
(HAT), a neglected tropical disease (NTD) that is endemic in 36 countries in sub-Saharan …

Synthetic dibenzylideneketones as promising anti-herpes simplex virus type 1 agents

TZ Oliveira, DP Fonseca, AH Dos Santos… - Archives of …, 2023 - Springer
New antiviral agents for the treatment of herpes simplex virus type 1 (HSV-1) infection, which
causes a highly prevalent and incurable disease, are needed. Here, we report for the first …