Impact of saturated compared with unsaturated dietary fat on insulin sensitivity, pancreatic β-cell function and glucose tolerance: a systematic review and meta …

M Lytrivi, CGDS Cauduro, J Kibanda, P Kristanto… - The American journal of …, 2023 - Elsevier
Background The impact of the dietary fat type on type 2 diabetes (T2D) remains unclear.
Objectives We aimed to evaluate the effects of replacing dietary saturated fatty acids (SFA) …

Effect of the Lipid Landscape on the Efficacy of Cell-Penetrating Peptides

F Zakany, IM Mándity, Z Varga, G Panyi, P Nagy… - Cells, 2023 - mdpi.com
Every cell biological textbook teaches us that the main role of the plasma membrane is to
separate cells from their neighborhood to allow for a controlled composition of the …

Ginsenoside Rb1 protects against diabetes-associated metabolic disorders in Kkay mice by reshaping gut microbiota and fecal metabolic profiles

R Zhou, D He, H Zhang, J Xie, S Zhang, X Tian… - Journal of …, 2023 - Elsevier
Abstract Ethnopharmacological relevance Panax quinquefolius Linn. is one of the most
valuable herbal medicine in the world for its broad health benefits, including anti-diabetes …

[图书][B] Saturated fatty acid and trans-fatty acid intake for adults and children: WHO guideline

World Health Organization - 2023 - books.google.com
his guideline provides updated, evidence-informed guidance on the intake of saturated fatty
acids and trans fatty acids to reduce the risk of diet-related noncommunicable diseases in …

A nutritional biomarker score of the Mediterranean diet and incident type 2 diabetes: Integrated analysis of data from the MedLey randomised controlled trial and the …

JG Sobiecki, F Imamura, CR Davis, SJ Sharp… - PLoS …, 2023 - journals.plos.org
Background Self-reported adherence to the Mediterranean diet has been modestly inversely
associated with incidence of type 2 diabetes (T2D) in cohort studies. There is uncertainty …

Pentadecanoic acid (C15: 0), an essential fatty acid, shares clinically relevant cell-based activities with leading longevity-enhancing compounds

S Venn-Watson, NJ Schork - Nutrients, 2023 - mdpi.com
Pentadecanoic acid (C15: 0) is an essential odd-chain saturated fatty acid with broad
activities relevant to protecting cardiometabolic, immune, and liver health. C15: 0 activates …

Fatty acids as histone deacetylase inhibitors: old biochemistry tales in a new life sciences town

MK Ediriweera - Drug Discovery Today, 2023 - Elsevier
Highlights•Fatty acids target the cancer epigenome.•Fatty acids are histone deacetylase
inhibitors.•Fatty acids exert anti-cancer effects.Histone acetylation is a key epigenetic event …

The lipidomic correlates of epigenetic aging across the adult lifespan: A population‐based study

D Liu, NA Aziz, EN Landstra, MMB Breteler - Aging Cell, 2023 - Wiley Online Library
Lipid signaling is involved in longevity regulation, but which specific lipid molecular species
affect human biological aging remains largely unknown. We investigated the relation …

Nontargeted metabolomics revealed novel association between serum metabolites and incident acute coronary syndrome: A Mendelian randomization study

G Qiu, Y Lin, Y Ouyang, M You, X Zhao… - Journal of the …, 2023 - Am Heart Assoc
Background This study was performed to identify metabolites associated with incident acute
coronary syndrome (ACS) and explore causality of the associations. Methods and Results …

Integrated lipids biomarker of the prediabetes and type 2 diabetes mellitus Chinese patients

J Yang, M Wang, D Yang, H Yan, Z Wang… - Frontiers in …, 2023 - frontiersin.org
Introduction Dyslipidemia is a hallmark of T2DM, and as such, analyses of lipid metabolic
profiles in affected patients have the potential to permit the development of an integrated …