Sulfobutylether-β-cyclodextrin: A functional biopolymer for drug delivery applications

CV Pardeshi, RV Kothawade, AR Markad… - Carbohydrate …, 2023 - Elsevier
Sulfobutylether β-cyclodextrin (SBE-β-CD) is a polyanionic cyclic oligosaccharide that
contains glucopyranose units forming a torus ring-like structure. SBE-β-CD is gifted with …

Challenges and opportunities in delivering oral peptides and proteins

H Peng, J Wang, J Chen, Y Peng, X Wang… - Expert opinion on …, 2023 - Taylor & Francis
Introduction Rapid advances in bioengineering enable the use of complex proteins as
therapeutic agents to treat diseases. Compared with conventional small molecule drugs …

Reduction-triggered polycyclodextrin supramolecular nanocage induces immunogenic cell death for improved chemotherapy

J Hu, M Liang, M Ye, J Xu, H Liu, X Zhang, W Sun… - Carbohydrate …, 2023 - Elsevier
Polycyclodextrin-based supramolecular nanoplatform crosslinked by stimuli-responsive
moiety shows great promise in cancer therapy owing to its superior bio-stability and feasible …

Piperine loaded metal organic frameworks reverse doxorubicin induced chemobrain in adult zebrafish

S Arora, V Kumar, L Kapil, AK Agrawal, A Singh… - Journal of Controlled …, 2023 - Elsevier
The study's primary goal was to enhance medicinal potential of piperine (PIP)-loaded
zeolitic imidazolate frameworks-8 (PIP@ ZIF-8) against doxorubicin (DOX)-induced …

Unveiling the complexation mechanism of phloretin with Sulfobutylether–β–cyclodextrin (Captisol®) and its impact on anticancer activity

N Khan, G Slathia, A Saneja - Journal of Molecular Liquids, 2023 - Elsevier
The incorporation of phloretin (PHL), a dihydrochalcone flavonoid, in functional foods is
usually hampered by its low aqueous solubility. In this regard, we investigated the impact of …

PEGylated erlotinib HCl injectable nanoformulation for improved bioavailability

H Bhargave, H Nijhawan, KS Yadav - AAPS PharmSciTech, 2023 - Springer
The present study was undertaken to synthesize PEGylated monomethoxy poly (ethylene
glycol)-poly (ε-Caprolactone)(mPEG-PCL) block copolymer and formulate Erlotinib HCl …

Curcumin-sulfobutyl-ether beta cyclodextrin inclusion complex: preparation, spectral characterization, molecular modeling, and antimicrobial activity

AB Sravani, M Shenoy K, B Chandrika… - Journal of …, 2023 - Taylor & Francis
Urinary tract infections (UTIs) caused by Gram-negative bacteria E. coli is responsible for 80–
90% of uncomplicated cases in women. The increased prevalence of antibiotic resistance …

Inclusion complex of chrysin with hydroxypropyl-β-cyclodextrin (HP-β-CD) preparation, characterization, and dissolution study

K Lavania, A Garg - BioNanoScience, 2023 - Springer
The objective of the study was to prepare and characterize the inclusion complex of chrysin
(CHR) with hydroxypropyl-β-cyclodextrin (HP-β-CD). The phase solubility study was …

[HTML][HTML] Piperine Loaded Drug Delivery Systems for Improved Biomedical Applications: Current Status and Future Directions

S Arora, B Singh, S Kumar, A Kumar, A Singh… - Health Sciences …, 2023 - Elsevier
About 42% of drugs with market acceptance and 92% of drugs in the discovery pipeline are
imperfectly aqueous soluble with insufficient intestinal absorption and will suffer from low …

Preparation and Characterization of Clopidogrel Bisulfate-hydroxypropyl-β-Cyclodextrin Mixed Inclusion Complex for Improved Intestinal Solubility and Anti …

A Singh, R Sharma, S Chaudhary, V Rana - Journal of Pharmaceutical …, 2023 - Elsevier
The study aimed to increase the intestinal solubility and absorption of orally bioavailable
clopidogrel-bisulfate (CPB) by complexing with hydroxypropyl-β-cyclodextrin (HCD) to form …