The cytochrome P450 (CYP) enzyme family is the major enzyme system catalyzing the
phase I metabolism of xenobiotics, including pharmaceuticals and toxic compounds in the …

Abstract The cytochrome P450 (CYP450) enzyme system is responsible for the metabolism
of more than two-thirds of xenobiotics. This review summarizes reports of a series of in silico …

Ginger is currently one of the most popular herbs commonly added to diverse foods,
beverages, and dietary supplements. We evaluated the ability of a well-characterized ginger …

Grapefruit juice, which discovered to interact with felodipine for the first time, is now known to
interact with more that 80 drugs. Statins are among the drugs that interact with grapefruit …

Nutraceuticals are products that are present in food, which apart from providing nutritive
value also act as potential drugs. They bestow physiological benefits or may protect against …

The objective of this chapter is to provide an overview of the design and conduct of clinical
pharmacokinetic (PK) studies when investigating extrinsic factors that may influence the PK …

The intake of food and drinks with orally administered medicines can significantly impact the
therapeutic efficacy or adverse side effects of a drug, posing barriers to effective therapeutic …

Docteur en Pharmacie Page 1 Année: 2023 Thèse N: 033 Influence de l’alimentation sur l’efficacite
des medicaments THESE Présentée et soutenue publiquement le : / /2023 PAR Monsieur …