The re-emergence of hepatitis E virus in Europe and vaccine development
G Zahmanova, K Takova, V Tonova, T Koynarski… - Viruses, 2023 - mdpi.com
Hepatitis E virus (HEV) is one of the leading causes of acute viral hepatitis. Transmission of
HEV mainly occurs via the fecal-oral route (ingesting contaminated water or food) or by …
HEV mainly occurs via the fecal-oral route (ingesting contaminated water or food) or by …
The Diagnosis, Pathophysiology, and Treatment of Chronic Hepatitis E Virus Infection—A Condition Affecting Immunocompromised Patients
S Takakusagi, S Kakizaki, H Takagi - Microorganisms, 2023 - mdpi.com
Hepatitis E is a zoonosis caused by hepatitis E virus (HEV), which was first discovered 40
years ago. Twenty million HEV infections worldwide are estimated each year. Most hepatitis …
years ago. Twenty million HEV infections worldwide are estimated each year. Most hepatitis …
Distinct disease features of acute and persistent genotype 3 hepatitis E virus infection in immunocompetent and immunosuppressed Mongolian gerbils
S Subramaniam, R Fares-Gusmao, S Sato… - PLoS …, 2023 - journals.plos.org
Hepatitis E virus (HEV) causes self-limited acute hepatitis in immunocompetent individuals
and can establish chronic infection in solid organ transplant recipients taking …
and can establish chronic infection in solid organ transplant recipients taking …
Targeting proteostasis of the HEV replicase to combat infection in preclinical models
F Zhang, LD Xu, Q Zhang, A Wang, X Yu, S Liu… - Journal of …, 2023 - Elsevier
Background & Aims Appropriate treatment options are lacking for hepatitis E virus (HEV)-
infected pregnant women and immunocompromised individuals. Thus, we aimed to identify …
infected pregnant women and immunocompromised individuals. Thus, we aimed to identify …
Emergence of resistance-associated variants during sofosbuvir treatment in chronically infected hepatitis E patients
A Gömer, M Klöhn, M Jagst, MK Nocke, S Pischke… - Hepatology, 2023 - journals.lww.com
Conclusions: In conclusion, viral population dynamics played a critical role during antiviral
treatment. High population diversity during sofosbuvir treatment led to the selection of …
treatment. High population diversity during sofosbuvir treatment led to the selection of …
[HTML][HTML] Janus kinase-inhibition modulates hepatitis E virus infection
V Kinast, I Andreica, G Ahrenstorf, A Gömer, C Elsner… - Antiviral research, 2023 - Elsevier
Hepatitis E virus (HEV) usually causes a self-limiting disease, but especially
immunocompromised individuals are at risk to develop a chronic and severe course of …
immunocompromised individuals are at risk to develop a chronic and severe course of …
Hepatitis a virus and hepatitis E virus as food-and waterborne pathogens—transmission routes and methods for detection in food
Foodborne viruses are an important threat to food safety and public health. Globally, there
are approximately 5 million cases of acute viral hepatitis due to hepatitis A virus (HAV) and …
are approximately 5 million cases of acute viral hepatitis due to hepatitis A virus (HAV) and …
Diagnostic and management strategies for chronic hepatitis E infection
F Abravanel, S Lhomme, O Marion… - Expert Review of Anti …, 2023 - Taylor & Francis
ABSTRACT Introduction Hepatitis E Virus (HEV) was initially thought to cause only acute
infections, but the discovery of chronic hepatitis E in immunocompromised patients has …
infections, but the discovery of chronic hepatitis E in immunocompromised patients has …
The PRMT5/WDR77 complex restricts hepatitis E virus replication
Hepatitis E virus (HEV) is one of the main pathogenic agents of acute hepatitis in the world.
The mechanism of HEV replication, especially host factors governing HEV replication is still …
The mechanism of HEV replication, especially host factors governing HEV replication is still …
Detection of HEV RNA using one-step real-time RT-PCR in farrow-to-finish pig farms in Bulgaria
GL Krumova-Valcheva, I Di Bartolo, RP Smith… - Pathogens, 2023 - mdpi.com
(1) Background: HEV is a zoonotic, foodborne pathogen. It is spread worldwide and
represents a public health risk. The aim of this study was to evaluate the presence of HEV …
represents a public health risk. The aim of this study was to evaluate the presence of HEV …