Amyotrophic lateral sclerosis (ALS) is a devastating disease caused by degeneration of
motor neurons. As with all major neurodegenerative disorders, development of disease …

Amyotrophic lateral sclerosis (ALS) is a rapidly progressive neurodegenerative disorder
affecting upper and lower motor neurons, with death resulting mainly from respiratory failure …

Interest in amyotrophic lateral sclerosis (ALS) biomarkers has grown exponentially over the
course of the last 25 years, with great hope that they might serve as tools to facilitate the …

Although the past two decades have produced exciting discoveries in the genetics and
pathology of amyotrophic lateral sclerosis (ALS), progress in developing an effective therapy …

Cerebral autosomal dominant arteriopathy with subcortical infarcts and
leukoencephalopathy (CADASIL) is the most common monogenic disorder of the cerebral …

Objective Amyotrophic lateral sclerosis (ALS) is a heterogeneous disease with a complex
etiology that lacks biomarkers predicting disease progression. The objective of this study …

In randomized clinical trials (RCTs) for Alzheimer's Disease (AD), cerebrospinal fluid (CSF)
and positron emission tomography (PET) biomarkers are currently used for the detection …

Simple Summary Since neuroaxonal damage and loss are observed in chemotherapy-
induced peripheral neuropathy (CIPN) and results in permanent disability, detecting and …

Abstract Background In Wilson's disease (WD), early neurological deterioration after
treatment initiation is associated with poor outcomes; however, data on this phenomenon …

Objective To investigate the relationship between serum levels of the neuroaxonal
degeneration biomarker neurofilament light chain (NFL) and phenotype in ALS. Materials …