Secondary brain injury after neurotrauma is comprised of a host of distinct, potentially
concurrent and interacting mechanisms that may exacerbate primary brain insult …

OBJECTIVES: Critically ill patients are at high risk of acute brain injury. Bedside
multimodality neuromonitoring techniques can provide a direct assessment of physiologic …

Importance While the relationship between persistent elevations in intracranial pressure
(ICP) and poorer outcomes is well established for patients with traumatic brain injury (TBI) …

Background: Targeting a cerebral perfusion pressure optimal for cerebral autoregulation
(CPPopt) has been gaining more attention to prevent secondary damage after acute …

Acute brain injury (ABI) covers various clinical entities that may require invasive mechanical
ventilation (MV) in the intensive care unit (ICU). The goal of MV, which is to protect the lung …

Increased intracranial pressure (ICP) causes disability and mortality in the neurointensive
care population. Current methods for monitoring ICP are invasive. We designed a deep …

Aneurysmal subarachnoid hemorrhage is a medical condition that can lead to intracranial
hypertension, negatively impacting patients' outcomes. This review article explores the …

Background The implementation of multimodality monitoring in the clinical management of
patients with disorders of consciousness (DoC) results in physiological measurements that …

Cerebral hypoxia is an important cause of secondary brain injury. Improving systemic
oxygenation may increase brain tissue oxygenation (PbtO2). The effects of increased …

Given the complexity of cerebral pathology in patients with acute brain injury, various
neuromonitoring strategies have been developed to better appreciate physiologic …