[HTML][HTML] New GABA-targeting therapies for the treatment of seizures and epilepsy: I. Role of GABA as a modulator of seizure activity and recently approved …
E Perucca, M Bialer, HS White - CNS drugs, 2023 - Springer
Abstract γ-Aminobutyric acid (GABA) is the most prevalent inhibitory neurotransmitter in the
mammalian brain and has been found to play an important role in the pathogenesis or the …
mammalian brain and has been found to play an important role in the pathogenesis or the …
Clinical efficacy and safety of Zuranolone (SAGE-217) in individuals with major depressive disorder
S Meshkat, KM Teopiz, JD Di Vincenzo… - Journal of Affective …, 2023 - Elsevier
Major depressive disorder (MDD) is a common mental disorder with a high rate of morbidity
and mortality. Dysfunctional signaling of gamma-aminobutyric acid (GABA) has been …
and mortality. Dysfunctional signaling of gamma-aminobutyric acid (GABA) has been …
Outcomes and treatment approaches for super-refractory status epilepticus: a systematic review and meta-analysis
CD Cornwall, T Krøigård, JSS Kristensen… - JAMA …, 2023 - jamanetwork.com
Importance Super-refractory status epilepticus (SRSE) is defined as status epilepticus (SE)
that continues or recurs 24 hours or more after the onset of anesthetic therapy or recurs on …
that continues or recurs 24 hours or more after the onset of anesthetic therapy or recurs on …
[HTML][HTML] Treatment of pediatric convulsive status epilepticus
LL Becker, A Gratopp, C Prager, CE Elger… - Frontiers in …, 2023 - frontiersin.org
Status epilepticus is one of the most common life-threatening neurological emergencies in
childhood with the highest incidence in the first 5 years of life and high mortality and …
childhood with the highest incidence in the first 5 years of life and high mortality and …
[HTML][HTML] Corticosteroids in childhood epilepsies: A systematic review
LL Becker, AM Kaindl - Frontiers in Neurology, 2023 - frontiersin.org
Corticosteroids have been used for the treatment of patients with epilepsy for more than 6
decades, based on the hypothesis of inflammation in the genesis and/or promotion of …
decades, based on the hypothesis of inflammation in the genesis and/or promotion of …
GABAergic Neurotransmission Abnormalities in Pharmacoresistant Epilepsy: Experimental and Human Studies
S Orozco-Suárez, IA Feria-Romero… - … in Epilepsy: From …, 2023 - Springer
Despite the fact that there are several drugs available for the treatment of epilepsy,
pharmacoresistance remains a major challenge in seizure control. Therefore, a significant …
pharmacoresistance remains a major challenge in seizure control. Therefore, a significant …
[PDF][PDF] GABAergic Neurotransmission Abnormalities inPharmacoresistant Epilepsy: Experimental andHuman Studies
IAFR SandraOrozco-Suárez - Pharmacoresistance in Epilepsy - researchgate.net
Despite the fact that there are several drugs available for the treatment of epilepsy,
pharmacoresistance remains a major challenge in seizure control. Therefore, a significant …
pharmacoresistance remains a major challenge in seizure control. Therefore, a significant …