[HTML][HTML] Pathogenesis of hypertension in metabolic syndrome: the role of fructose and salt
M Soleimani, S Barone, H Luo, K Zahedi - International Journal of …, 2023 - mdpi.com
Metabolic syndrome is manifested by visceral obesity, hypertension, glucose intolerance,
hyperinsulinism, and dyslipidemia. According to the CDC, metabolic syndrome in the US …
hyperinsulinism, and dyslipidemia. According to the CDC, metabolic syndrome in the US …
Salt sensitivity includes effects on immune cell signalling and metabolism
DN Müller, S Geisberger, M Kleinewietfeld… - Nature Reviews …, 2023 - nature.com
Excess salt (sodium chloride) intake is a risk factor for hypertension and is attributed to
increasing rates of morbidity and mortality from cardiovascular diseases. Salt sensitivity is …
increasing rates of morbidity and mortality from cardiovascular diseases. Salt sensitivity is …
Seizure occurrence is linked to multiday cycles in diverse physiological signals
Objective The factors that influence seizure timing are poorly understood, and seizure
unpredictability remains a major cause of disability. Work in chronobiology has shown that …
unpredictability remains a major cause of disability. Work in chronobiology has shown that …
[HTML][HTML] Tissue sodium accumulation induces organ inflammation and injury in chronic kidney disease
Y Ito, T Sun, H Tanaka, M Yamaguchi… - International Journal of …, 2023 - mdpi.com
High salt intake is a primary cause of over-hydration in chronic kidney disease (CKD)
patients. Inflammatory markers are predictors of CKD mortality; however, the pathogenesis …
patients. Inflammatory markers are predictors of CKD mortality; however, the pathogenesis …
[HTML][HTML] The kidney, volume homeostasis and osmoregulation in space: current perspective and knowledge gaps
RHG Olde Engberink, PJ van Oosten, T Weber… - npj …, 2023 - nature.com
Although we have sent humans into space for more than 50 years crucial questions
regarding kidney physiology, volume regulation and osmoregulation remain unanswered …
regarding kidney physiology, volume regulation and osmoregulation remain unanswered …
[HTML][HTML] It is strongly recommended to not conduct, fund, or publish research studies that use spot urine samples with estimating equations to assess individuals' …
NRC Campbell, PK Whelton, M Orias… - Journal of …, 2023 - journals.lww.com
Spot urine samples with estimating equations have been used to assess individuals' sodium
(salt) intake in association with health outcomes. There is large random and systematic error …
(salt) intake in association with health outcomes. There is large random and systematic error …
Skin regulation of salt and blood pressure and potential clinical implications
K Martin, ND Toussaint, SJ Tan, TD Hewitson - Hypertension Research, 2023 - nature.com
Sodium chloride, as salt, gives rise to hypertension. Nevertheless, individual susceptibility to
the ramifications of sodium chloride is heterogeneous. The conventional nephron-centric …
the ramifications of sodium chloride is heterogeneous. The conventional nephron-centric …
High salt intake activates the hypothalamic–pituitary–adrenal axis, amplifies the stress response, and alters tissue glucocorticoid exposure in mice
HM Costello, G Krilis, C Grenier, D Severs… - Cardiovascular …, 2023 - academic.oup.com
Aims High salt intake is common and contributes to poor cardiovascular health. Urinary
sodium excretion correlates directly with glucocorticoid excretion in humans and …
sodium excretion correlates directly with glucocorticoid excretion in humans and …
Thiazide diuretics are back in CKD: the case of chlorthalidone
Sodium and volume excess is the fundamental risk factor underlying hypertension in chronic
kidney disease (CKD) patients, who represent the prototypical population characterized by …
kidney disease (CKD) patients, who represent the prototypical population characterized by …
Effects of pediatric chronic kidney disease and its etiology on tissue sodium concentration: a pilot study
Background Sodium-23 magnetic resonance imaging (23Na MRI) allows non-invasive
assessment of tissue sodium concentration ([Na+]). Age and chronic kidney disease (CKD) …
assessment of tissue sodium concentration ([Na+]). Age and chronic kidney disease (CKD) …