Interactions between Intestinal Homeostasis and NAD+ Biology in Regulating Incretin Production and Postprandial Glucose Metabolism

T Nagahisa, S Kosugi, S Yamaguchi - Nutrients, 2023 - mdpi.com
The intestine has garnered attention as a target organ for developing new therapies for
impaired glucose tolerance. The intestine, which produces incretin hormones, is the central …

Advancements in diabetes technology are outpacing the evidence

M Rickson, EE Wright Jr, A Bindal… - Diabetes Technology & …, 2023 - liebertpub.com
Diabetes technologies such as continuous glucose monitoring (CGM) continue to evolve at
an increasingly rapid pace. Seventeen new CGM devices have been introduced to the …

Effects of the timing of acute mulberry leaf extract intake on postprandial glucose metabolism in healthy adults: a randomised, placebo-controlled, double-blind study

M Takahashi, Y Mineshita, J Yamagami… - European Journal of …, 2023 - nature.com
Abstract Background/Objectives Glucose tolerance is controlled by the internal clock and is
worse in the evening. From a chrononutrition perspective, diabetes prevention requires …

Precision prevention of diabetes

WH Herman, W Ye - Diabetes Care, 2023 - Am Diabetes Assoc
Prediabetes is defined as glycemia that is higher than normal but not high enough to warrant
a diagnosis of diabetes. While it is not a disease in its own right, prediabetes is a risk factor …

[HTML][HTML] A randomized clinical trial comparing low-fat with precision nutrition–based diets for weight loss: impact on glycemic variability and HbA1c

AY Kharmats, C Popp, L Hu, L Berube, M Curran… - The American journal of …, 2023 - Elsevier
Background Recent studies have demonstrated considerable interindividual variability in
postprandial glucose response (PPGR) to the same foods, suggesting the need for more …

[HTML][HTML] Long-term effects of lowering postprandial glucose level on cardiovascular outcomes in early-stage diabetic patients with coronary artery disease: 10-year …

Y Kataoka, S Yasuda, Y Asaumi, S Honda… - Journal of Diabetes and …, 2023 - Elsevier
Aims To elucidate the long-term cardiovascular benefit of lowering postprandial
hyperglycemia (PPG) in early-stage T2DM patients. Methods This 10-year post-trial follow …

Synergistic enhancement of glucagon-like peptide-1 release by γ-aminobutyric acid and L-phenylalanine in enteroendocrine cells—searching active ingredients in a …

H Noguchi, N Kohda, H Hara… - Bioscience, Biotechnology …, 2023 - academic.oup.com
This study investigated the glucagon-like peptide-1 (GLP-1)-releasing activity of an aqueous
extract (ZeinS) from corn zein protein and aimed to identify the active compounds …

Health inequality in eight adverse outcomes over a 25-year period in a multi-ethnic population in New Zealand population with impaired glucose tolerance and/or …

Z Wang, D Yu, UL Osuagwu, K Pickering… - Clinical …, 2023 - Taylor & Francis
Purpose We aimed to examine socioeconomic inequality (SI) in cause-specific outcomes
among adults with impaired glucose tolerance (IGT) and/or Impaired fasting glucose (IFG) in …

Effects of mulberry twig alkaloids (Sangzhi alkaloids) and metformin on blood glucose fluctuations in combination with premixed insulin-treated patients with type 2 …

Z Meng, C Xu, H Liu, X Gao, X Li, W Lin, X Ma… - Frontiers in …, 2023 - frontiersin.org
Introduction We aimed to evaluated the effect of premixed insulin (Ins), premixed insulin
combined with metformin (Ins+ Met) or mulberry twig alkaloids (Ins+ SZ-A) on blood glucose …

Pharmacokinetics, pharmacodynamics, and safety of prandial oral insulin (N11005) in healthy subjects

Q Pan, X Wang, W Li, X Chen, Y Zhuang… - Frontiers in …, 2023 - frontiersin.org
Aims To verify whether the oral insulin N11005 is administered as a prandial insulin by
assessing the pharmacokinetics (PK), pharmacodynamics (PD), and safety profiles of …