Recent advances in non-small cell lung cancer targeted therapy; an update review
Lung cancer continues to be the leading cause of cancer-related death worldwide. In the last
decade, significant advancements in the diagnosis and treatment of lung cancer, particularly …
decade, significant advancements in the diagnosis and treatment of lung cancer, particularly …
At the crossroads of immunotherapy for oncogene-addicted subsets of NSCLC
I Otano, AC Ucero, J Zugazagoitia… - Nature reviews Clinical …, 2023 - nature.com
Non-small-cell lung cancer (NSCLC) has become a paradigm of precision medicine, with
the discovery of numerous disease subtypes defined by specific oncogenic driver mutations …
the discovery of numerous disease subtypes defined by specific oncogenic driver mutations …
Agnostic approvals in oncology: getting the right drug to the right patient with the right genomics
V Tateo, PV Marchese, V Mollica, F Massari… - Pharmaceuticals, 2023 - mdpi.com
(1) Background: The oncology field has drastically changed with the advent of precision
medicine, led by the discovery of druggable genes or immune targets assessed through next …
medicine, led by the discovery of druggable genes or immune targets assessed through next …
[HTML][HTML] Non-small cell lung carcinoma (NSCLC): Implications on molecular pathology and advances in early diagnostics and therapeutics
Continuous revision of the histologic and stage-wise classification of lung cancer by the
World Health Organization (WHO) provides the foundation for therapeutic advances by …
World Health Organization (WHO) provides the foundation for therapeutic advances by …
Understanding and targeting resistance mechanisms in cancer
Resistance to cancer therapies has been a commonly observed phenomenon in clinical
practice, which is one of the major causes of treatment failure and poor patient survival. The …
practice, which is one of the major causes of treatment failure and poor patient survival. The …
Targeted therapy for cancers: from ongoing clinical trials to FDA-approved drugs
HY Choi, JE Chang - International Journal of Molecular Sciences, 2023 - mdpi.com
The development of targeted therapies has revolutionized cancer treatment, offering
improved efficacy with reduced side effects compared with traditional chemotherapy. This …
improved efficacy with reduced side effects compared with traditional chemotherapy. This …
Targeted therapy for lung cancer: Beyond EGFR and ALK
M Herrera‐Juárez, C Serrano‐Gómez… - Cancer, 2023 - Wiley Online Library
Precision oncology comprises the set of strategies that aim to design the best cancer
treatment based on tumor biology. A recognized subset of patients with non‐small cell lung …
treatment based on tumor biology. A recognized subset of patients with non‐small cell lung …
Biomarker Testing in Patients With Unresectable Advanced or Recurrent Non–Small Cell Lung Cancer
T Sakamoto, T Matsubara, T Takahama… - JAMA Network …, 2023 - jamanetwork.com
Importance Biomarker testing for driver mutations is essential for selecting appropriate non–
small cell lung cancer (NSCLC) treatment but is insufficient. Objective To investigate the …
small cell lung cancer (NSCLC) treatment but is insufficient. Objective To investigate the …
[HTML][HTML] EGFR exon 20 insertion mutations and ERBB2 mutations in lung cancer: a narrative review on approved targeted therapies from oral kinase inhibitors to …
D Sentana-Lledo, E Academia, H Viray… - Translational Lung …, 2023 - ncbi.nlm.nih.gov
EGFR exon 20 insertion mutations and ERBB2 mutations in lung cancer: a narrative review
on approved targeted therapies from oral kinase inhibitors to antibody-drug conjugates - PMC …
on approved targeted therapies from oral kinase inhibitors to antibody-drug conjugates - PMC …
Liquid biopsies in lung cancer
M Kemper, C Krekeler, K Menck, G Lenz, G Evers… - Cancers, 2023 - mdpi.com
Simple Summary Liquid biopsy has recently been introduced as a novel method in cancer
diagnostics. It is less invasive for patients than conventional tissue biopsies, as the assay …
diagnostics. It is less invasive for patients than conventional tissue biopsies, as the assay …