Plants and Plant‐Derived Molecules as Natural Immunomodulators

M Zebeaman, MG Tadesse, RK Bachheti… - BioMed research …, 2023 - Wiley Online Library
Background. Nowadays, the immunomodulatory properties of plants have been studied
extensively with greater interest due to increasing awareness and combating the severity of …

Improving access to therapy for patients with inborn errors of immunity: a call to action

MJ Dorsey, A Condino-Neto - The Journal of Allergy and Clinical …, 2023 - Elsevier
Breakthroughs in sequencing technology, targeted immunotherapy, and immune
reconstituting treatment have increased the pool of patients with inborn errors of immunity …

SARS-CoV-2 infection and response to COVID-19 vaccination in patients with primary immunodeficiencies

R Paris - The Journal of Infectious Diseases, 2023 - academic.oup.com
Primary immunodeficiencies (PIDs) are heterogeneous, rare disorders that increase
susceptibility to infection and/or immune dysregulation. Individuals with certain PIDs are at …

Severity of SARS-CoV-2 infection in children with inborn errors of immunity (primary immunodeficiencies): a systematic review

S Alhumaid, KM Al Mutared, Z Al Alawi, Z Sabr… - Allergy, Asthma & …, 2023 - Springer
Background Inborn errors of immunity (IEIs) are considered significant challenges for
children with IEIs, their families, and their medical providers. Infections are the most common …

Cellular immune response to SARS-CoV-2 in patients with primary antibody deficiencies

D Mizera, R Dziedzic, A Drynda… - Frontiers in …, 2023 - frontiersin.org
Introduction Primary antibody deficiencies (PAD) are inborn defects of the immune system
that result in increased susceptibility to infections. Despite the reduced response to …

Inborn errors of immunity—the Sri Lankan experience 2010–2022

D Dasanayake, J Bustamante… - Journal of clinical …, 2023 - Springer
Purpose Inborn errors of immunity (IEI) are typically monogenic. Data from the Indian
subcontinent are relatively scarce. This paper evaluates IEI diagnosed in Sri Lanka …

Large-scale deep learning analysis to identify adult patients at risk for combined and common variable immunodeficiencies

G Papanastasiou, G Yang, DI Fotiadis… - Communications …, 2023 - nature.com
Background Primary immunodeficiency (PI) is a group of heterogeneous disorders resulting
from immune system defects. Over 70% of PI is undiagnosed, leading to increased mortality …

Challenges of diagnosing Mendelian susceptibility to mycobacterial diseases in South Africa

D Scholtz, T Jooste, M Möller, A van Coller… - International Journal of …, 2023 - mdpi.com
Inborn errors of immunity (IEI) are genetic disorders with extensive clinical presentations.
They can range from increased susceptibility to infections to significant immune …

Value of diagnostic vaccination in diagnosis of humoral inborn errors of immunity

L Hlongwa, J Peter, E Mayne - Human Immunology, 2023 - Elsevier
Inborn errors of immunity (IEIs) or primary immunodeficiency diseases, are disorders caused
by genetic defects affecting immune function. Clinically, IEI presents mainly as recurrent or …

Clinical outcome of coronavirus disease 2019 in patients with primary antibody deficiencies

T Milota, J Smetanova, J Bartunkova - Pathogens, 2023 - mdpi.com
In 2019, the novel coronavirus, SARS-CoV-2, caused a worldwide pandemic, affecting more
than 630 million individuals and causing 6.5 million deaths. In the general population …