Human stem cells for cardiac disease modeling and preclinical and clinical applications—are we on the road to success?
CD Correia, A Ferreira, MT Fernandes, BM Silva… - Cells, 2023 - mdpi.com
Cardiovascular diseases (CVDs) are pointed out by the World Health Organization (WHO)
as the leading cause of death, contributing to a significant and growing global health and …
as the leading cause of death, contributing to a significant and growing global health and …
Exosome-bearing hydrogels and cardiac tissue regeneration
H Amini, AR Namjoo, MT Narmi, N Mardi… - Biomaterials …, 2023 - spj.science.org
Background In recent years, cardiovascular disease in particular myocardial infarction (MI)
has become the predominant cause of human disability and mortality in the clinical setting …
has become the predominant cause of human disability and mortality in the clinical setting …
Cardiac regeneration–Past advancements, current challenges, and future directions
Cardiovascular disease is the leading cause of mortality and morbidity worldwide. Despite
improvements in the standard of care for patients with heart diseases, including innovation …
improvements in the standard of care for patients with heart diseases, including innovation …
Stem cell therapy for acute myocardial infarction: Mesenchymal Stem Cells and induced Pluripotent Stem Cells
D Clavellina, W Balkan, JM Hare - Expert opinion on biological …, 2023 - Taylor & Francis
Introduction Acute myocardial infarction (AMI) remains a leading cause of death in the
United States. The limited capacity of cardiomyocytes to regenerate and the restricted …
United States. The limited capacity of cardiomyocytes to regenerate and the restricted …
Effect of once versus twice intracoronary injection of allogeneic-derived mesenchymal stromal cells after acute myocardial infarction: BOOSTER-TAHA7 randomized …
Background Mesenchymal stromal cell (MSC) transplantation can improve the left
ventricular ejection fraction (LVEF) after an acute myocardial infarction (AMI). Transplanted …
ventricular ejection fraction (LVEF) after an acute myocardial infarction (AMI). Transplanted …
Safety and outcomes analysis: transcatheter implantation of autologous angiogenic cell precursors for the treatment of cardiomyopathy
JR Schubart, A Zare, RM Fernandez-de-Castro… - Stem Cell Research & …, 2023 - Springer
Background Stem cell transplantation is an emerging therapy for severe cardiomyopathy,
proffering stem cell recruitment, anti-apoptosis, and proangiogenic capabilities. Angiogenic …
proffering stem cell recruitment, anti-apoptosis, and proangiogenic capabilities. Angiogenic …
[HTML][HTML] The recent advances in cell delivery approaches, biochemical and engineering procedures of cell therapy applied to coronary heart disease
J Ma, W Wang, W Zhang, D Xu, J Ding, F Wang… - Biomedicine & …, 2023 - Elsevier
Cell therapy is an important topic in the field of regeneration medicine that is gaining
attention within the scientific community. However, its potential for treatment in coronary …
attention within the scientific community. However, its potential for treatment in coronary …
Microvascular obstruction identifies a subgroup of patients who benefit from stem cell therapy following ST-elevation myocardial infarction
SJ Davidson, J Roncalli, D Surder, R Corti… - American Heart …, 2023 - Elsevier
Background Microvascular obstruction (MVO) is associated with greater infarct size, adverse
left-ventricular (LV) remodeling and reduced ejection fraction following ST-elevation …
left-ventricular (LV) remodeling and reduced ejection fraction following ST-elevation …
Preventive effect of bone marrow mononuclear cell transplantation on acute myocardial infarction-induced heart failure: a meta-analysis of randomized controlled trials
Purpose Heart failure (HF) is a major complication of acute myocardial infarction (AMI).
Transplantation of bone marrow mononuclear cells (BM-MNC) in the setting of AMI has been …
Transplantation of bone marrow mononuclear cells (BM-MNC) in the setting of AMI has been …
[HTML][HTML] Healing the ischaemic heart: a critical review of stem cell therapies
D Tonkin, A Yee-Goh, R Katare - Reviews in Cardiovascular Medicine, 2023 - imrpress.com
Ischaemic heart disease (IHD) remains the leading cause of mortality worldwide. Current
pharmaceutical treatments focus on delaying, rather than preventing disease progression …
pharmaceutical treatments focus on delaying, rather than preventing disease progression …