Cancer is one of the major causes of mortality and morbidity worldwide. Substantial
research efforts have been made to develop new chemical entities with improved anticancer …

Over the past few decades, a significant number of anticancer drugs have been developed,
both natural and synthetic. Thiazole, a 5-membered distinctive heterocyclic motif with …

In the search for new anticancer agents, we synthesized a new series of thiazole derivatives
carried on thiadiazole-oxadiazole hybrid. Final compounds (5a–5i) were analyzed via 1H …

Two 1, 3, 4-oxadiazole-2-thione-N-Mannich derivatives, specifically 5-(4-chlorophenyl)-3-[(2-
trifluoromethylphenylamino) methyl]-1, 3, 4-oxadiazole-2 (3H)-thione (1) and 5-(4 …

Cancer is one of the life-threatening diseases accountable for millions of demises globally.
The inadequate effectiveness of the existing chemotherapy and its harmful effects has …

Quinoline and its analogues are found in various natural products, many of which are active
pharmacophores with significant bioactivities. This article discussed the plethora of …

A new library of diverse isoxazole contained 1, 3-oxazole-1, 3, 4-oxadiazole heterocyclic
hybrids have been synthesized (9a-j). The compounds were characterized by 1 HNMR, 13 …

Cancer is one of the major causes of death across the world. Cancer is a broad word that
encompasses a wide range of illnesses that can affect any part of the body. Cancer research …

Abstract A new series of 1, 3, 4-oxadiazole bearing pyrimidine-pyrazine derivatives (9a–j)
was developed and examined for their preliminary anticancer effects against four human …

A new library of bis-thiazol-1, 2, 4-triazinehybrids having 1, 3, 4-oxadiazoles (10a–j) has
been designed and synthesized. They were examined for their preliminary anticancer …