Diabetic cardiomyopathy: Early diagnostic biomarkers, pathogenetic mechanisms, and therapeutic interventions

JL Huo, Q Feng, S Pan, WJ Fu, Z Liu, Z Liu - Cell death discovery, 2023 - nature.com
Diabetic cardiomyopathy (DCM) mainly refers to myocardial metabolic dysfunction caused
by high glucose, and hyperglycemia is an independent risk factor for cardiac function in the …

Current understanding of structural and molecular changes in diabetic cardiomyopathy

MS Akhtar, SS Alavudeen, A Raza, MT Imam… - Life Sciences, 2023 - Elsevier
Diabetic Mellitus has been characterized as the most prevalent disease throughout the
globe associated with the serious morbidity and mortality of vital organs. Cardiomyopathy is …

Iron accumulation and lipid peroxidation: implication of ferroptosis in diabetic cardiomyopathy

X Yan, Y Xie, H Liu, M Huang, Z Yang, D An… - Diabetology & Metabolic …, 2023 - Springer
Diabetic cardiomyopathy (DC) is a serious heart disease caused by diabetes. It is unrelated
to hypertension and coronary artery disease and can lead to heart insufficiency, heart failure …

NLRP3 Inflammasome Involvement in Heart, Liver, and Lung Diseases—A Lesson from Cytokine Storm Syndrome

C Napodano, V Carnazzo, V Basile, K Pocino… - International Journal of …, 2023 - mdpi.com
Inflammation and inflammasomes have been proposed as important regulators of the host–
microorganism interaction, playing a key role in morbidity and mortality due to the …

Association of serum uric acid and fasting plasma glucose with cognitive function: a cross-sectional study

Z Yuan, H Liu, R Zhou, S Gu, K Wu, Z Huang, Q Zhong… - BMC geriatrics, 2023 - Springer
Background The combined effect of serum uric acid (SUA) and blood glucose on cognition
has not been explored. This study aimed to examine the separate and combined association …

The Influences of Perinatal Androgenic Exposure on Cardiovascular and Metabolic Disease of Offspring of PCOS

F Guo, S Mao, Y Long, B Zhou, L Gao, H Huang - Reproductive Sciences, 2023 - Springer
Hyperandrogenism is an endocrine disorder affecting a large population of reproductive-
aged women, thus proportionally high number of fetuses are subjected to prenatal …

Cardioprotective role of A-cycloglycosylated derivative of Rubiadin in diabetic cardiomyopathy in rats

M Zhu, Y Yu, Y Song, C Wang, Z Miao, B Chen… - International …, 2023 - Elsevier
Diabetic cardiomyopathy (DCM) is a kind of idiopathic heart disease, which is one of the
main complications of diabetes and seriously threatens the life of diabetic patients …

Vitamin D attenuates diabetic myocardial injury via the Erbb4/ferroptosis axis

H Song, Y Miao, Y Zhang, L Zhang, H Chen, L Tang… - bioRxiv, 2023 - biorxiv.org
Background: Hyperglycemia and hyperlipidemia lead to the ferroptosis, well as the
phosphorylation of Erbb4, and thereby increase the risk of cardiac hypertrophy. Thus, our …

Interplay of Angiotensin Peptides, Vasopressin and Insulin in the Heart: Altered Interactions in Obesity and Diabetes Mellitus

E Szczepańska-Sadowska - 2023 - preprints.org
The heart serves as the pivotal organ generating rhythmic contractions allowing blood
ejection from the ventricles and its circulation in the cardiovascular system. Contractions of …

A study on the role of oxidative stress and protein kinase signalling in hyperglycaemia induced cardiac remodelling

N Amtha - 2023 - open.uct.ac.za
Background Almost one-third of all deaths in patients with uncontrolled diabetes mellitus
and hyperglycaemia are due to cardiovascular diseases. Chronic exposure of the heart to …