Multifaceted role of mTOR (mammalian target of rapamycin) signaling pathway in human health and disease
The mammalian target of rapamycin (mTOR) is a protein kinase that controls cellular
metabolism, catabolism, immune responses, autophagy, survival, proliferation, and …
metabolism, catabolism, immune responses, autophagy, survival, proliferation, and …
Recent advances in single-cell RNA-sequencing of primary and metastatic clear cell renal cell carcinoma
AM Alchahin, I Tsea, N Baryawno - Cancers, 2023 - mdpi.com
Simple Summary In recent years, several therapeutic advances have been made in clear
cell renal cell carcinoma (ccRCC) resulting in novel treatment regimens of increased …
cell renal cell carcinoma (ccRCC) resulting in novel treatment regimens of increased …
A phase i trial of bevacizumab and temsirolimus in combination with valproic acid in advanced solid tumors
BE Nelson, AM Tsimberidou, X Fu, S Fu… - The …, 2023 - academic.oup.com
Background Preclinical models suggest synergy between anti-angiogenesis therapy,
mammalian target of rapamycin (mTOR), and histone deacetylase inhibitors to promote …
mammalian target of rapamycin (mTOR), and histone deacetylase inhibitors to promote …
Pulmonary toxicity of mTOR inhibitors. Comparisons of two populations: Solid organ recipients and cancer patients
S Gendarme, J Pastré, EM Billaud, L Gibault… - Therapies, 2023 - Elsevier
Introduction Mammalian target of rapamycin (mTOR) inhibitors-associated pneumonitis
(mTOR-IP) has long been described in solid organ recipients (T) patients but more recently …
(mTOR-IP) has long been described in solid organ recipients (T) patients but more recently …