Robot-assisted TAMIS: a systematic review of feasibility and outcomes

PCH Jakobsen, PM Krarup, KK Jensen… - Surgical …, 2023 - Springer
Background In the advancement of transanal local excision, robot-assisted transanal
minimal invasive surgery is the newest development. In the confined area of the rectum …

Neoadjuvant chemotherapy, excision, and observation for early rectal cancer: the phase II NEO trial (CCTG CO. 28) primary end point results

HF Kennecke, CJ O'Callaghan, JM Loree… - Journal of Clinical …, 2023 - ascopubs.org
PURPOSE Organ-sparing therapy for early-stage I/IIA rectal cancer is intended to avoid
functional disturbances or a permanent ostomy associated with total mesorectal excision …

CLASSICA: Validating artificial intelligence in classifying cancer in real time during surgery

A Moynihan, N Hardy, J Dalli, F Aigner… - Colorectal …, 2023 - Wiley Online Library
Aim Treatment pathways for significant rectal polyps differ depending on the underlying
pathology, but pre‐excision profiling is imperfect. It has been demonstrated that differences …

Endoscopic and trans-anal local excision vs. radical resection in the treatment of early rectal cancer: A systematic review and network meta-analysis

C Kwik, T El-Khoury, N Pathma-Nathan… - International Journal of …, 2023 - Springer
Purpose The management of early-stage rectal cancer in clinical practice is controversial.
The aim of this network meta-analysis was to compare oncological and postoperative …

Chemoradiation and local excision versus total mesorectal excision for T2N0 rectal cancer: comparison of short-and long-term outcomes from 2 prospective studies

PB Lynn, MJM Van der Valk, YHM Claassen… - Annals of …, 2023 - journals.lww.com
Objective: Compare oncological long-term and short-term outcomes between patients with
distal cT2NO rectal cancer treated with chemoradio-therapy and local excision (CRT+ LE) …

Endoscopy and MRI for restaging early rectal cancer after neoadjuvant treatment

RCH Stijns, J Leijtens, E de Graaf, SP Bach… - Colorectal …, 2023 - Wiley Online Library
Aim Chemoradiotherapy (CRT) has great potential to downstage rectal cancer. Response
assessment has been investigated in locally advanced rectal cancer but not in early stage …

Clinical T2N0 rectal cancer treated with neoadjuvant chemoradiotherapy plus local excision

T Suzuki, S Sadahiro, K Okada, H Miyakita, T Ogimi… - Oncology, 2023 - karger.com
Introduction: Total mesorectal excision is the standard treatment for clinical T2 (cT2) rectal
cancer; however, this procedure can result in postoperative dysfunction, decreased quality …

[HTML][HTML] Efficacy of preoperative chemoradiotherapy in patients with cT2N0 distal rectal cancer

MY Park, CS Yu, TW Kim, JH Kim, J Park… - Annals of …, 2023 - ncbi.nlm.nih.gov
Purpose This study was designed to determine the feasibility of preoperative
chemoradiotherapy (PCRT) in patients with clinical T2N0 distal rectal cancer. Methods …

Is local excision an appropriate treatment modality in patients presenting with early-stage (cT1 N0 M0) rectal adenocarcinoma?

S Roat-Shumway, C Tonelli, M Singer, T Cohn… - Surgery, 2023 - Elsevier
Background Prior studies evaluating the safety and efficacy of local excision relative to
surgical resection in early-stage rectal adenocarcinoma have primarily included low rectal …

Predictors and outcomes of positive surgical margins after local excision of clinical T1 rectal cancer: A National Cancer Database analysis

MR Freund, N Horesh, SH Emile, Z Garoufalia, R Gefen… - Surgery, 2023 - Elsevier
Background Transanal local excision and the use of specialized platforms has become
increasingly popular for early-stage rectal cancer. Predictors and outcomes of positive …