Stem cells have self-renewal capacities and the ability to give rise to differentiated cells
thereby sustaining tissues during homeostasis and injury. This structural hierarchy extends …

Lung cancer is indeed a major cause of cancer‐related deaths worldwide. The development
of tumors involves a complex interplay of genetic, epigenetic, and environmental factors …

Solid tumors have developed robust ferroptosis resistance. The mechanism underlying
ferroptosis resistance regulation in solid tumors, however, remains elusive. Here, we report …

The prevalence of obesity has reached pandemic levels worldwide, leading to a lower
quality of life and higher health costs. Obesity is a major risk factor for noncommunicable …

MicroRNAs (miRNAs) are secreted from cells as either protein-bound or enclosed in
extracellular vesicles. Circulating liver-derived miRNAs are modifiable by weight-loss or …

Background The drug delivery for treatment of glioblastoma multiforme (GBM) has been
unsatisfactory mainly due to the drug resistance and low targeting efficiency. The selective …

Cellular senescence, an evolutionarily conserved mechanism that prevents the proliferation
of damaged cells, is a very relevant cellular response involved in both physiological and …

Colorectal cancer (CRC) is among the leading causes of cancer mortality. The lifetime risk of
developing CRC is about 5% in adult males and females. CRC is usually diagnosed at an …

Introduction Lymphoma is a common canine cancer with translational relevance to human
disease. Diffuse large B-cell lymphoma (DLBCL) is the most frequent subtype, contributing …

A global increase in the incidence of pancreatic cancer (PanCa) presents a major concern
and health burden. The traditional tissue-based diagnostic techniques provided a major way …