Acquired Hemophilia A: An update on the etiopathogenesis, diagnosis, and treatment

E Zanon - Diagnostics, 2023 - mdpi.com
Acquired haemophilia A (AHA) is a rare bleeding disorder caused by inhibitory
autoantibodies against coagulation factor VIII (FVIII). AHA is a disease that most commonly …

[HTML][HTML] Emicizumab in acquired hemophilia A: Pros and cons of a new approach to the prevention and treatment of bleeding

S Pasca, E Zanon, PM Mannucci, F Peyvandi - Blood Transfusion, 2023 - ncbi.nlm.nih.gov
Emicizumab, a monoclonal bispecific antibody that mimics the function of activated factor VIII
(FVIII), is currently licensed for prophylactic use in patients with congenital hemophilia A with …

[HTML][HTML] A prospective, multicenter, open-label phase III study of emicizumab prophylaxis in patients with acquired hemophilia A

M Shima, K Amano, Y Ogawa, K Yoneyama… - Journal of Thrombosis …, 2023 - Elsevier
Background Emicizumab is a bispecific antibody that mimics the cofactor function of
activated factor (F) VIII. It prevents bleeds in patients with congenital hemophilia A …

Clot waveform analysis for monitoring hemostasis

K Nogami - Seminars in Thrombosis and Hemostasis, 2023 - thieme-connect.com
Clot waveform analysis (CWA) is a recently developed global coagulation assessment,
based on the continuous observation of changes in light transmittance, absorbance, or light …

Investigating a signal of acquired hemophilia associated with COVID-19 vaccination: a systematic case review

M Franchini, E Cappello, G Valdiserra… - … in Thrombosis and …, 2023 - thieme-connect.com
Acquired hemophilia A (AHA), a rare but life-threatening disorder, most commonly occurs in
older people and during pregnancy. During the coronavirus disease 2019 (COVID-19) …

Risk factors, treatment and survival rates of late‐onset acquired haemophilia a: a cohort study from the Shizuoka Kokuho database

A Shoji‐Asahina, E Nakatani, Y Imaichi, E Ohata… - …, 2023 - Wiley Online Library
Abstract Introduction Acquired haemophilia A (AHA) is a rare disease. The risk factors have
yet to be studied. Aim We aimed to identify risk factors for late‐onset AHA in Japan. Methods …

Drug‐associated acquired hemophilia A: an analysis based on 185 cases from the WHO pharmacovigilance database

K Konstantinov, C Dolladille, B Gillet, J Alexandre… - …, 2023 - Wiley Online Library
Abstract Introduction Acquired hemophilia A (AHA) is a rare autoimmune hemorrhagic
disease occurring in several underlying conditions. Drug‐associated AHA (D‐AHA) is poorly …

Management of acquired haemophilia A in severe Covid‐19: Haemostatic bridging with emicizumab to keep the balance between bleeding and thrombosis

G Gelbenegger, L Traby, N Rahimi… - British Journal of …, 2023 - Wiley Online Library
Acquired haemophilia A (AHA) is an autoimmune bleeding disorder caused by
autoantibodies blocking coagulation factor VIII (FVIII). Haemostatic management of AHA and …

Cases of acquired hemophilia A following COVID‐19 vaccines: Cogent safety signal or possible reporting/detection bias? Preliminary evidence from Tuscany, Italy

G Roberto, O Paoletti, S Ferraro… - … and Drug Safety, 2023 - Wiley Online Library
Purpose Several case reports of acquired hemophilia A (AHA) following COVID‐19 vaccines
were recently published. A possible increased incidence of AHA during the COVID‐19 …

Emicizumab for the treatment of acquired hemophilia A: Retrospective review of a single‐institution experience

EC Chen, W Gibson, P Temoczko, NT Connell… - …, 2023 - Wiley Online Library
Abstract Introduction Acquired haemophilia A (AHA) is a rare and potentially life‐threatening
bleeding disorder arising from autoantibodies that inhibit coagulation factor VIII (FVIII) …