Personalizing neoadjuvant immune-checkpoint inhibition in patients with melanoma

MW Lucas, JM Versluis, EA Rozeman… - Nature Reviews Clinical …, 2023 - nature.com
Neoadjuvant immune-checkpoint inhibition is a promising emerging treatment approach for
patients with surgically resectable macroscopic stage III melanoma. The neoadjuvant setting …

Sentinel lymph node assessment in melanoma: current state and future directions

TW Cheng, E Hartsough, A Giubellino - Histopathology, 2023 - Wiley Online Library
Assessment of sentinel lymph node status is an important step in the evaluation of patients
with melanoma for both prognosis and therapeutic management. Pathologists have an …

[HTML][HTML] Deep learning detection of melanoma metastases in lymph nodes

P Jansen, DO Baguer, N Duschner, JLC Arrastia… - European Journal of …, 2023 - Elsevier
Background In melanoma patients, surgical excision of the first draining lymph node, the
sentinel lymph node (SLN), is a routine procedure to evaluate lymphogenic metastases …

[HTML][HTML] Has the advent of modern adjuvant systemic therapy for melanoma rendered sentinel node biopsy unnecessary?

AHR Varey, JF Thompson, JR Howle, SN Lo… - European Journal of …, 2023 - Elsevier
The prognostic value of sentinel node biopsy (SNB) is well established and SNB was
therefore adopted as a requirement for pathological staging of melanomas> 1 mm thick in …

[HTML][HTML] Debating sentinel lymph node biopsy for melanoma in the modern adjuvant era

X Zhang, L Ferris, MB Faries, JJ Luke - Journal of Clinical …, 2023 - ncbi.nlm.nih.gov
Malignant melanoma was projected to have an incidence of> 99,000 cases in the United
States in 2022 and is one of the few cancers for which incidence is rising. 1 Current …

Predictors of sentinel lymph node metastasis in very thin invasive melanomas

H Kakish, J Sun, DX Zheng, FA Ahmed… - British Journal of …, 2023 - academic.oup.com
Abstract Background Melanomas< 0.8 mm in Breslow depth have less than a 5% risk for
nodal positivity. Nonetheless, nodal positivity is prognostic for this group. Early identification …

Sentinel lymph node biopsy in patients with T1a cutaneous malignant melanoma: a multicenter cohort study

AB Shannon, CE Sharon, RJ Straker III, MJ Carr… - Journal of the American …, 2023 - Elsevier
Background Sentinel lymph node biopsy is not routinely recommended for T1a cutaneous
melanoma due to the overall low risk of positivity. Prognostic factors for positive sentinel …

Sentinel lymph node biopsy for extremity and truncal soft tissue sarcomas: a systematic review of the literature

EZ Keung, KJ Krause, J Maxwell, CD Morris… - Annals of surgical …, 2023 - Springer
Background Regional lymph node metastasis (RLNM) occurs infrequently in patients with
soft tissue sarcoma (STS), although certain STS subtypes have a higher propensity for …

Role of sentinel lymph node biopsy for skin cancer based on clinical studies

S Ishizuki, Y Nakamura - Cancers, 2023 - mdpi.com
Simple Summary Sentinel lymph nodes are the first regional lymph nodes to receive lymph
fluid from the primary cancer, sentinel lymph node biopsy (SLNB) can detect occult nodal …

The current treatment trends and survival patterns in melanoma patients with positive sentinel lymph node biopsy (SLNB): a multicenter nationwide study

M Ziętek, P Teterycz, J Wierzbicki, M Jankowski… - Cancers, 2023 - mdpi.com
Simple Summary In this study, the treatment trends and survival among 557 patients with
sentinel lymph node biopsy (SLNB)-positive melanomas were analyzed. We have …