Chemical derivatization strategy for mass spectrometry‐based lipidomics

F Xia, JB Wan - Mass Spectrometry Reviews, 2023 - Wiley Online Library
Lipids, serving as the structural components of cellular membranes, energy storage, and
signaling molecules, play the essential and multiple roles in biological functions of …

Mass spectrometry‐based strategies for single‐cell metabolomics

R Hu, Y Li, Y Yang, M Liu - Mass Spectrometry Reviews, 2023 - Wiley Online Library
Single cell analysis has drawn increasing interest from the research community due to its
capability to interrogate cellular heterogeneity, allowing refined tissue classification and …

Supplementation with Tribulus Terrestris extract exhibits protective effects on MCAO rats via modulating inflammation-related metabolic and signaling pathways

H Zhang, W Guo, X Li, S Xie, Y Liu, G Chen, Y Wang… - ACS …, 2023 - ACS Publications
The extract of Tribulus terrestris (TT) has been used as a component of several nutritional
supplements for enhancing human vitality. However, its protective effect on ischemic stroke …

Investigating the in vivo effect of Tribulus terrestris extract in middle cerebral artery occlusion rats using LC–MS‐based metabolomics combined with molecular …

X Li, W Guo, L Zhao, D Xu, X Xu, Y Han… - Biomedical …, 2023 - Wiley Online Library
Tribulus terrestris L. fruit (TT) is a traditional Chinese herbal medicine used to treat ischemic
stroke (IS). This study aimed to investigate the protective effect of TT extract, named TT15, on …

Integrative metabolomics and network pharmacology to study the preventative impact of dioscin treatment on hyperuricemia

D Yu, J Fu, Y Wang, F Lu, P Chen… - Biomedical …, 2023 - Wiley Online Library
This work aims to combine network pharmacology and metabolomics to explore the
mechanism of action of dioscin on hyperuricemia (HUA). The preventative impact of dioscin …

Exploring the in vitro anti‐inflammatory activity of gross saponins of Tribulus terrestris L. fruit by using liquid chromatography‐mass spectrometry‐based cell …

X Xu, W Guo, L Zhao, Y Sun, D Xu… - Journal of …, 2023 - Wiley Online Library
Our previous studies confirmed the efficacy of gross saponins of Tribulus terrestris L. fruit in
treating cerebral ischemia. This study aimed to investigate the related mechanisms in vitro …

[HTML][HTML] BoxCar data-dependent acquisition improves the MS/MS coverage in liquid chromatography-mass spectrometry-based metabolomics analysis

Y Wang, S Liu - Arabian Journal of Chemistry, 2023 - Elsevier
Tandem mass spectrometry (MS2) information is always applied for compound identification
or annotation in liquid chromatography-mass spectrometry (LC-MS)-based untargeted …

Protonated and Sodiated Cyclophosphamide Fragmentation Pathways Evaluation by Infrared Multiple Photon Dissociation Spectroscopy

AS Fernandes, G Obeid, TJN Laureno… - The Journal of …, 2023 - ACS Publications
Cyclophosphamide (CP or CTX) is a widely used antineoplastic agent, and the evaluation of
its efficacy and its impacts on the environment are dependent on tandem mass spectrometry …

Spectrométrie de mobilité ionique pour la lipidomique du plasma humain: vers la mesure standardisée de sections efficaces de collision

A George - 2023 - theses.hal.science
La métabolomique consiste en l'étude des petites molécules d'un organisme vivant, pour
permettre une meilleure compréhension des systèmes biologiques. L'identification des …

[PDF][PDF] Development of New Bioinformatic Tools to Improve Mass Spectrometry-based Analysis of the Lipidome

MIA Balaguer - 2023 - roderic.uv.es
Que la presente memoria, titulada “Development of new bioinformatic tools to improve mass
spectrometry-based analysis of the lipidome.”, corresponde al trabajo realizado bajo su …