[HTML][HTML] Nutrition and exercise interventions to improve body composition for persons with overweight or obesity near retirement age: a systematic review and network …

D Eglseer, M Traxler, S Embacher, L Reiter… - Advances in …, 2023 - Elsevier
The retirement phase is an opportunity to integrate healthy (nutrition/exercise) habits into
daily life. We conducted this systematic review to assess which nutrition and exercise …

Nutrients, physical activity, and mitochondrial dysfunction in the setting of metabolic syndrome

GO Lemos, RS Torrinhas, DL Waitzberg - Nutrients, 2023 - mdpi.com
Metabolic syndrome (MetS) is a cluster of metabolic risk factors for diabetes, coronary heart
disease, non-alcoholic fatty liver disease, and some tumors. It includes insulin resistance …

Effects of different doses of exercise and diet-induced weight loss on beta-cell function in type 2 diabetes (DOSE-EX): a randomized clinical trial

GE Legaard, MPP Lyngbæk, TP Almdal, K Karstoft… - Nature …, 2023 - nature.com
Diet-induced weight loss is associated with improved beta-cell function in people with type 2
diabetes (T2D) with remaining secretory capacity. It is unknown if adding exercise to diet …

The potential of fasting-mimicking diet as a preventive and curative strategy for Alzheimer's disease

V Boccardi, M Pigliautile, AG Guazzarini, P Mecocci - Biomolecules, 2023 - mdpi.com
This review examines the potential of fasting-mimicking diets (FMDs) in preventing and
treating Alzheimer's disease (AD). FMDs are low-calorie diets that mimic the physiological …

Determining the role of novel metabolic pathways in driving intracranial pressure reduction after weight loss

Z Alimajstorovic, JL Mitchell, A Yiangou… - Brain …, 2023 - academic.oup.com
Idiopathic intracranial hypertension, a disease classically occurring in women with obesity,
is characterized by raised intracranial pressure. Weight loss leads to the reduction in …

Insights into the development of insulin resistance: Unraveling the interaction of physical inactivity, lipid metabolism and mitochondrial biology

RM Handy, GP Holloway - Frontiers in Physiology, 2023 - frontiersin.org
While impairments in peripheral tissue insulin signalling have a well-characterized role in
the development of insulin resistance and type 2 diabetes (T2D), the specific mechanisms …

Ceramides are decreased after liraglutide treatment in people with type 2 diabetes: a post hoc analysis of two randomized clinical trials

A Wretlind, VR Curovic, A de Zawadzki… - Lipids in Health and …, 2023 - Springer
Background Specific ceramides have been identified as risk markers for cardiovascular
disease (CVD) years before onset of disease. Treatment with the glucagon-like peptide-1 …

[HTML][HTML] What is the optimal type and dose of physical activity for colorectal cancer prevention?

ST Orange - Best Practice & Research Clinical Gastroenterology, 2023 - Elsevier
Epidemiological evidence shows that higher levels of physical activity reduce the relative
risk of colon cancer by up to 20%. To design optimal physical activity interventions for …

An M dwarf accompanied by a close-in giant orbiter with SPECULOOS

AHMJ Triaud, G Dransfield, T Kagetani… - Monthly Notices of …, 2023 - academic.oup.com
In the last decade, a dozen close-in giant planets have been discovered orbiting stars with
spectral types ranging from M0 to M4, a mystery since known formation pathways do not …

Both moderate-and high-intensity exercise training increase intramyocellular lipid droplet abundance and modify myocellular distribution in adults with obesity

MW Schleh, C Ahn, BJ Ryan… - American Journal …, 2023 - journals.physiology.org
Exercise training modifies lipid metabolism in skeletal muscle, but the effect of exercise
training on intramyocellular lipid droplet (LD) abundance, size, and intracellular distribution …