Inflammasomes are critical sentinels of the innate immune system that respond to threats to
the host through recognition of distinct molecules, known as pathogen-or damage …

According to the endosymbiotic theory, most of the DNA of the original bacterial
endosymbiont has been lost or transferred to the nucleus, leaving a much smaller (∼ 16 kb …

Inflammasomes are a group of protein complex located in cytoplasm and assemble in
response to a wide variety of pathogen‐associated molecule patterns, damage‐associated …

Psoriasis is an inflammatory skin disease whose pathophysiology is attributed to both innate
and adaptive immune cells and molecules. Despite the crucial roles of the immune system in …

Autoimmune skin diseases are understood as conditions in which the adaptive immune
system with autoantigen-specific T cells and autoantibody-producing B cells reacting against …

Simple Summary This comprehensive review focuses on the role of epigenetics in oral
squamous cell carcinoma (OSCC), a prevalent type of oral cancer. The review highlights the …

Hepatocytes, the predominant cellular constituents of the liver, exhibit the highest
mitochondrial density within the human body. Remarkably, experimental insights from the …

Pathogenic dsDNA prompts AIM2 assembly leading to the formation of the inflammasome, a
multimeric complex that triggers the inflammatory response. The recognition of foreign …

The hematopoietic interferon-inducible nuclear (HIN) domain of the PYHIN family of proteins
recognizes double-stranded DNA (dsDNA) through different dsDNA-binding modes. These …

The biggest challenge to immune control of HIV infection is the rapid within-host viral
evolution, which allows selection of viral variants that escape from T cell and antibody …