[HTML][HTML] Management of sepsis and septic shock: what have we learned in the last two decades?

S Kamath, H Hammad Altaq, T Abdo - Microorganisms, 2023 - mdpi.com
Sepsis is a clinical syndrome encompassing physiologic and biological abnormalities
caused by a dysregulated host response to infection. Sepsis progression into septic shock is …

[HTML][HTML] An updated “norepinephrine equivalent” score in intensive care as a marker of shock severity

Y Kotani, A Di Gioia, G Landoni, A Belletti, AK Khanna - Critical Care, 2023 - Springer
Vasopressors and fluids are the cornerstones for the treatment of shock. The current
international guidelines on shock recommend norepinephrine as the first-line vasopressor …

[HTML][HTML] VDAC2 malonylation participates in sepsis-induced myocardial dysfunction via mitochondrial-related ferroptosis

H She, L Tan, Y Du, Y Zhou, N Guo… - … Journal of Biological …, 2023 - ncbi.nlm.nih.gov
Sepsis-induced myocardial dysfunction (SIMD) is a prevalent and severe form of organ
dysfunction with elusive underlying mechanisms and limited treatment options. In this study …

Is left ventricular systolic dysfunction associated with increased mortality among patients with sepsis and septic shock?

S Dugar, R Sato, S Chawla, JY You, X Wang, R Grimm… - Chest, 2023 - Elsevier
Background The impact of left ventricular (LV) systolic function on outcomes in patients with
sepsis and septic shock remains uncertain. The association, if any, may be nonlinear …

Ligand-based shielding effect induced efficient near-infrared electrochemiluminescence of gold nanoclusters and its sensing application

Y Nie, Y Zhang, W Cao, Y Chai, R Yuan - Analytical Chemistry, 2023 - ACS Publications
Preparing high-efficiency ECL gold nanoclusters (Au NCs) still faces a serious challenge
due to the poor stability of co-reactant radicals in aqueous media. Herein, we report a ligand …

The efficacy and safety of vasopressors for septic shock patients: A systemic review and network meta-analysis

L Jia, P Wang, C Li, J Xie - Shock, 2023 - journals.lww.com
Background: Septic shock is a distributive shock with decreased systemic vascular
resistance and MAP. Septic shock contributes to the most common causes of death in the …

[HTML][HTML] Vasopressin in Sepsis and other Shock States: state of the art

R García-Álvarez, R Arboleda-Salazar - Journal of Personalized …, 2023 - mdpi.com
This review of the use of vasopressin aims to be comprehensive and highly practical, based
on the available scientific evidence and our extensive clinical experience with the drug. It …

[HTML][HTML] Circulatory shock in adults in emergency department

AK Pannu - Turkish Journal of Emergency Medicine, 2023 - journals.lww.com
Circulatory shock is a common condition that carries high morbidity and mortality. This
review aims to update the critical steps in managing common types of shock in adult patients …

[HTML][HTML] A randomized controlled trial of norepinephrine plus dobutamine versus epinephrine as first-line vasoactive agents in children with fluid refractory cold septic …

KK Banothu, J Sankar, UV Kumar, P Gupta… - Critical Care …, 2023 - journals.lww.com
OBJECTIVES: Our objective was to compare norepinephrine plus dobutamine versus
epinephrine as the first-line agent in children with fluid refractory cold septic shock. DESIGN …

Therapeutic dilemmas in mixed septic-cardiogenic shock

DU Jassir, AH Chaanine, S Desai, I Rajapreyar… - The American Journal of …, 2023 - Elsevier
Sepsis is an increasing cause of decompensation in patients with chronic heart failure with
reduced or preserved ejection fraction. Sepsis and decompensated heart failure results in a …