[HTML][HTML] Precise excision of HTLV-1 provirus with a designer-recombinase

T Rojo-Romanos, J Karpinski, S Millen, N Beschorner… - Molecular Therapy, 2023 - cell.com
The human T cell leukemia virus type 1 (HTLV-1) is a pathogenic retrovirus that persists as a
provirus in the genome of infected cells and can lead to adult T cell leukemia (ATL) …

[HTML][HTML] Mechanisms of innate immune sensing of HTLV-1 and viral immune evasion

S Mohanty, EW Harhaj - Pathogens, 2023 - mdpi.com
Human T lymphotropic virus-1 (HTLV-1) was the first identified oncoretrovirus, which infects
and establishes a persistent infection in approximately 10–20 million people worldwide …

Design peptide and multi-epitope protein vaccine candidates against monkeypox virus using reverse vaccinology approach: an in-silico study

HR Jahantigh, B Shahbazi, H Gouklai… - Journal of …, 2023 - Taylor & Francis
Monkeypox is a zoonotic virus that has recently affected different countries worldwide. On
July 23, 2022, the WHO declared the outbreak of monkeypox as a public health emergency …

HTLV-1 biofilm polarization maintained by tetraspanin CD82 is required for efficient viral transmission

C Arone, S Martial, J Burlaud-Gaillard, MI Thoulouze… - Mbio, 2023 - Am Soc Microbiol
The human T-lymphotropic virus type 1 (HTLV-1) is an oncogenic retrovirus whose
transmission relies primarily on cell-to-cell contacts as cell-free viruses are poorly infectious …

STLV-1 Commonly targets neurons in the brain of asymptomatic non-human primates

B Rocamonde, S Alais, R Pelissier, V Moulin… - Mbio, 2023 - Am Soc Microbiol
The human T-cell leukemia virus (HTLV)-1 is responsible for an aggressive
neurodegenerative disease (HAM/TSP) and multiple neurological alterations. The capacity …

Cell culture evaluation suggests widely available HIV drugs will make effective HTLV-1 prophylactics

MD Kalemera, GN Maertens - 2023 - preprints.org
With an estimated 10 million people infected, the deltaretrovirus human T-cell lymphotropic
virus type 1 (HTLV-1) is the second most prevalent pathogenic retrovirus in humans after …

Upregulation of host genes during disease progression in bovine leukemia virus infection is independent of overexpression of viral transcriptional regulators in vitro

A Nishimori, K Andoh, Y Matsuura, J Kohara… - Archives of …, 2023 - Springer
Bovine leukemia virus (BLV) is a member of the genus Deltaretrovirus within the family
Retroviridae that infects bovine B cells, causing persistent lymphocytosis and enzootic …

HTLV-1 Rex hijacks UPF1 in a CRM1 dependent manner, leading to NMD inhibition and revealing unexpected proviral roles of UPF1

L Prochasson, M Mghezzi-Habellah, A Roisin, M Palma… - bioRxiv, 2023 - biorxiv.org
The hijacking of CRM1 export is an important step of the retroviral replication cycle. Here, we
investigated the consequences of this hijacking for the host. During HTLV-1 infection, we …

Tetraspanin CD82 maintains HTLV-1 biofilm polarization and is required for efficient viral transmission

C Arone, S Martial, J Burlaud-Gaillard, MI Thoulouze… - bioRxiv, 2023 - biorxiv.org
The human T-lymphotropic virus type-1 (HTLV-1) is an oncogenic retrovirus whose
transmission relies primarily on cell-to-cell contacts as cell-free viruses are poorly infectious …

[图书][B] Neuropilin-1 Is Upregulated by HTLV-1 bZIP Factor and Inhibits Cell-to-Cell Transmission of HTLV-1

WL Kendle - 2023 - search.proquest.com
Human T-cell Leukemia Virus Type 1 (HTLV-1) is the etiologic agent of devastating
diseases, including adult T-cell leukemia/lymphoma (ATL) and HTLV-1-associated …