Metals to combat antimicrobial resistance

A Frei, AD Verderosa, AG Elliott, J Zuegg… - Nature Reviews …, 2023 - nature.com
Bacteria, similar to most organisms, have a love–hate relationship with metals: a specific
metal may be essential for survival yet toxic in certain forms and concentrations. Metal ions …

Ruthenium-based photoactivated chemotherapy

S Bonnet - Journal of the American Chemical Society, 2023 - ACS Publications
Ruthenium (II) polypyridyl complexes form a vast family of molecules characterized by their
finely tuned photochemical and photophysical properties. Their ability to undergo excited …

Recent advances in metal complexes for antimicrobial photodynamic therapy

TW Rees, PY Ho, J Hess - ChemBioChem, 2023 - Wiley Online Library
Antimicrobial resistance (AMR) is a growing global problem with more than 1 million deaths
due to AMR infection in 2019 alone. New and innovative therapeutics are required to …

Ruthenium (II) Polypyridyl Complexes and Metronidazole Derivatives: A Powerful Combination in the Design of Photoresponsive Antibacterial Agents Effective under …

GE Giacomazzo, L Conti, C Fagorzi, M Pagliai… - Inorganic …, 2023 - ACS Publications
Ruthenium (II) polypyridyl complexes (RPCs) are gaining momentum in photoactivated
chemotherapy (PACT), thanks to the possibility of overcoming the classical reliance on …

Clearing an ESKAPE pathogen in a model organism; a polypyridyl ruthenium (II) complex theranostic that treats a resistant Acinetobacter baumannii infection in …

K Smitten, HM Southam, S Fairbanks… - … A European Journal, 2023 - Wiley Online Library
In previous studies we have described the therapeutic action of luminescent dinuclear
ruthenium (II) complexes based on the tetrapyridylphenazine, tpphz, bridging ligand on …

Applications of light emitting diodes and their mechanism for food preservation

T Ramesh, U Hariram, A Srimagal… - Journal of Food …, 2023 - Wiley Online Library
In the food sector, light emitting diodes (LEDs) have a wide range of uses, including
improving food production, extending the shelf life of perishables, and—most importantly …

High quantum efficiency ruthenium coordination complex photosensitizer for improved radiation-activated Photodynamic Therapy

AK Azad, L Lilge, NH Usmani, JD Lewis… - Frontiers in …, 2023 - frontiersin.org
Traditional external light-based Photodynamic Therapy (PDT)'s application is limited to the
surface and minimal thickness tumors because of the inefficiency of light in penetrating deep …

Computational Assessment of a Dual-Action Ru (II)-Based Complex: Photosensitizer in Photodynamic Therapy and Intercalating Agent for Inducing DNA Damage

F Ponte, S Scoditti, P Barretta, G Mazzone - Inorganic Chemistry, 2023 - ACS Publications
A combined quantum-mechanical and classical molecular dynamics study of a recent Ru (II)
complex with potential dual anticancer action is reported here. The main basis for the …

Complejos de Ru (II) con 2, 2'-biimidazol para sensores químicos luminiscentes y fotosensibilización de especies reactivas de oxígeno (ROS)

J Quílez Alburquerque - 2023 - docta.ucm.es
En primer lugar, me gustaría expresar mi agradecimiento a mis directores de tesis, el Prof.
Guillermo Orellana y la Prof. Ana Belén Descalzo. Gracias a los dos por haber confiado en …

Novel Approaches of Photodynamic Therapy for Lung Cancer

SR Chamberlain - 2023 - search.proquest.com
Lung cancer remains the leading cause of cancer related deaths. Photodynamic therapy
(PDT) is a promising adjuvant option for patients with lung cancer. The focus of this thesis …