ZBTB2 links p53 deficiency to HIF‐1‐mediated hypoxia signaling to promote cancer aggressiveness

S Koyasu, S Horita, K Saito, M Kobayashi, H Ishikita… - EMBO …, 2023 - embopress.org
Aberrant activation of the hypoxia‐inducible transcription factor HIF‐1 and dysfunction of the
tumor suppressor p53 have been reported to induce malignant phenotypes and therapy …

In vivo optical imaging of tumor stromal cells with hypoxia‐inducible factor activity

H Miyabara, R Hirano, S Watanabe… - Cancer …, 2023 - Wiley Online Library
Tumors contain various stromal cells, such as immune cells, endothelial cells, and
fibroblasts, which contribute to the development of a tumor‐specific microenvironment …