[HTML][HTML] Viral vectored vaccines: design, development, preventive and therapeutic applications in human diseases
S Wang, B Liang, W Wang, L Li, N Feng… - Signal transduction and …, 2023 - nature.com
Human diseases, particularly infectious diseases and cancers, pose unprecedented
challenges to public health security and the global economy. The development and …
challenges to public health security and the global economy. The development and …
Isothermal nucleic acid amplification technology for rapid detection of virus
While the research field and industrial market of in vitro diagnosis (IVD) thrived during and
post the COVID-19 pandemic, the development of isothermal nucleic acid amplification test …
post the COVID-19 pandemic, the development of isothermal nucleic acid amplification test …
[HTML][HTML] Recombinant vesicular stomatitis virus–vectored vaccine induces long-lasting immunity against Nipah virus disease
The emergence of the novel henipavirus, Langya virus, received global attention after the
virus sickened over three dozen people in China. There is heightened concern that …
virus sickened over three dozen people in China. There is heightened concern that …
[HTML][HTML] Antibodies against the Ebola virus soluble glycoprotein are associated with long-term vaccine-mediated protection of non-human primates
Summary The 2013 Ebola epidemic in Central and West Africa heralded the emergence of
wide-spread, highly pathogenic viruses. The successful recombinant vector vaccine against …
wide-spread, highly pathogenic viruses. The successful recombinant vector vaccine against …
Single-dose VSV-based vaccine protects against Kyasanur Forest disease in nonhuman primates
B Bhatia, TL Tang-Huau, F Feldmann, PW Hanley… - Science …, 2023 - science.org
Kyasanur Forest disease virus (KFDV) is an endemic arbovirus in western India mainly
transmitted by hard ticks of the genus Haemaphysalis. KFDV causes Kyasanur Forest …
transmitted by hard ticks of the genus Haemaphysalis. KFDV causes Kyasanur Forest …
[HTML][HTML] Rapid protection of nonhuman primates against Marburg virus disease using a single low-dose VSV-based vaccine
Background Marburg virus (MARV) is the causative agent of Marburg virus disease (MVD)
which has a case fatality rate up to∼ 90% in humans. Recently, there were cases reported …
which has a case fatality rate up to∼ 90% in humans. Recently, there were cases reported …
A highly attenuated panfilovirus VesiculoVax vaccine rapidly protects nonhuman primates against Marburg virus and 3 species of Ebola virus
C Woolsey, V Borisevich, KN Agans… - The Journal of …, 2023 - academic.oup.com
Abstract Background The family Filoviridae consists of several virus members known to
cause significant mortality and disease in humans. Among these, Ebola virus (EBOV) …
cause significant mortality and disease in humans. Among these, Ebola virus (EBOV) …
[HTML][HTML] YF17D-vectored Ebola vaccine candidate protects mice against lethal surrogate Ebola and yellow fever virus challenge
V Lemmens, L Kelchtermans, S Debaveye, W Chiu… - npj Vaccines, 2023 - nature.com
Ebola virus (EBOV) and related filoviruses such as Sudan virus (SUDV) threaten global
public health. Effective filovirus vaccines are available only for EBOV, yet restricted to …
public health. Effective filovirus vaccines are available only for EBOV, yet restricted to …
Advances in mRNA vaccines for viral diseases
Y Huang, X Zhu, X Guo, Y Zhou, D Liu… - Journal of Medical …, 2023 - Wiley Online Library
Since the onset of the pandemic caused by severe acute respiratory syndrome coronavirus
2, messenger RNA (mRNA) vaccines have demonstrated outstanding performance. mRNA …
2, messenger RNA (mRNA) vaccines have demonstrated outstanding performance. mRNA …
[HTML][HTML] Baseline gene signatures of reactogenicity to Ebola vaccination: a machine learning approach across multiple cohorts
PC Gonzalez Dias Carvalho… - Frontiers in …, 2023 - frontiersin.org
Introduction The rVSVDG-ZEBOV-GP (Ervebo®) vaccine is both immunogenic and
protective against Ebola. However, the vaccine can cause a broad range of transient …
protective against Ebola. However, the vaccine can cause a broad range of transient …