[HTML][HTML] Viral vectored vaccines: design, development, preventive and therapeutic applications in human diseases

S Wang, B Liang, W Wang, L Li, N Feng… - Signal transduction and …, 2023 - nature.com
Human diseases, particularly infectious diseases and cancers, pose unprecedented
challenges to public health security and the global economy. The development and …

Isothermal nucleic acid amplification technology for rapid detection of virus

Z Wei, X Wang, H Feng, F Ji, D Bai… - Critical Reviews in …, 2023 - Taylor & Francis
While the research field and industrial market of in vitro diagnosis (IVD) thrived during and
post the COVID-19 pandemic, the development of isothermal nucleic acid amplification test …

[HTML][HTML] Recombinant vesicular stomatitis virus–vectored vaccine induces long-lasting immunity against Nipah virus disease

C Woolsey, V Borisevich, AC Fears… - The Journal of …, 2023 - Am Soc Clin Investig
The emergence of the novel henipavirus, Langya virus, received global attention after the
virus sickened over three dozen people in China. There is heightened concern that …

[HTML][HTML] Antibodies against the Ebola virus soluble glycoprotein are associated with long-term vaccine-mediated protection of non-human primates

BM Gunn, RP McNamara, L Wood, S Taylor… - Cell reports, 2023 - cell.com
Summary The 2013 Ebola epidemic in Central and West Africa heralded the emergence of
wide-spread, highly pathogenic viruses. The successful recombinant vector vaccine against …

Single-dose VSV-based vaccine protects against Kyasanur Forest disease in nonhuman primates

B Bhatia, TL Tang-Huau, F Feldmann, PW Hanley… - Science …, 2023 - science.org
Kyasanur Forest disease virus (KFDV) is an endemic arbovirus in western India mainly
transmitted by hard ticks of the genus Haemaphysalis. KFDV causes Kyasanur Forest …

[HTML][HTML] Rapid protection of nonhuman primates against Marburg virus disease using a single low-dose VSV-based vaccine

KL O'Donnell, F Feldmann, B Kaza, CS Clancy… - …, 2023 - thelancet.com
Background Marburg virus (MARV) is the causative agent of Marburg virus disease (MVD)
which has a case fatality rate up to∼ 90% in humans. Recently, there were cases reported …

A highly attenuated panfilovirus VesiculoVax vaccine rapidly protects nonhuman primates against Marburg virus and 3 species of Ebola virus

C Woolsey, V Borisevich, KN Agans… - The Journal of …, 2023 - academic.oup.com
Abstract Background The family Filoviridae consists of several virus members known to
cause significant mortality and disease in humans. Among these, Ebola virus (EBOV) …

[HTML][HTML] YF17D-vectored Ebola vaccine candidate protects mice against lethal surrogate Ebola and yellow fever virus challenge

V Lemmens, L Kelchtermans, S Debaveye, W Chiu… - npj Vaccines, 2023 - nature.com
Ebola virus (EBOV) and related filoviruses such as Sudan virus (SUDV) threaten global
public health. Effective filovirus vaccines are available only for EBOV, yet restricted to …

Advances in mRNA vaccines for viral diseases

Y Huang, X Zhu, X Guo, Y Zhou, D Liu… - Journal of Medical …, 2023 - Wiley Online Library
Since the onset of the pandemic caused by severe acute respiratory syndrome coronavirus
2, messenger RNA (mRNA) vaccines have demonstrated outstanding performance. mRNA …

[HTML][HTML] Baseline gene signatures of reactogenicity to Ebola vaccination: a machine learning approach across multiple cohorts

PC Gonzalez Dias Carvalho… - Frontiers in …, 2023 - frontiersin.org
Introduction The rVSVDG-ZEBOV-GP (Ervebo®) vaccine is both immunogenic and
protective against Ebola. However, the vaccine can cause a broad range of transient …