Diagnosis and treatment of bipolar disorder: a review

AA Nierenberg, B Agustini, O Köhler-Forsberg, C Cusin… - JAMA, 2023 - jamanetwork.com
Importance Bipolar disorder affects approximately 8 million adults in the US and
approximately 40 million individuals worldwide. Observations Bipolar disorder is …

Evaluation of brain-body health in individuals with common neuropsychiatric disorders

YE Tian, MA Di Biase, PE Mosley, MK Lupton… - JAMA …, 2023 - jamanetwork.com
Importance Physical health and chronic medical comorbidities are underestimated,
inadequately treated, and often overlooked in psychiatry. A multiorgan, systemwide …

Long-term lithium therapy: side effects and interactions

E Ferensztajn-Rochowiak, JK Rybakowski - Pharmaceuticals, 2023 - mdpi.com
Lithium remains the drug of first choice for prophylactic treatment of bipolar disorder,
preventing the recurrences of manic and depressive episodes. The longitudinal experiences …

Absolute and relative risks of kidney outcomes associated with lithium vs valproate use in Sweden

A Bosi, CM Clase, L Ceriani, A Sjölander… - JAMA Network …, 2023 - jamanetwork.com
Importance Among patients with bipolar disorder, discordant findings have been published
on the nephrotoxic effects of lithium therapy. Objective To quantify absolute and relative risks …

[HTML][HTML] Reimagining safe lithium applications in the living environment and its impacts on human, animal, and plant system

N Shakoor, M Adeel, MA Ahmad, M Zain… - Environmental Science …, 2023 - Elsevier
Lithium's (Li) ubiquitous distribution in the environment is a rising concern due to its rapid
proliferation in the modern electronic industry. Li enigmatic entry into the terrestrial food …

Association of polygenic score and the involvement of cholinergic and glutamatergic pathways with lithium treatment response in patients with bipolar disorder

AT Amare, A Thalamuthu, KO Schubert… - Molecular …, 2023 - nature.com
Lithium is regarded as the first-line treatment for bipolar disorder (BD), a severe and
disabling mental health disorder that affects about 1% of the population worldwide …

Natural small molecule-induced polymer hydrogels with inherent antioxidative ability and conductivity for neurogenesis and functional recovery after spinal cord injury

F Wang, J Du, H Qiao, D Liu, D Guo, J Chen… - Chemical Engineering …, 2023 - Elsevier
Spinal cord injury (SCI) is a permanent disabling condition of the central nervous system.
The secondary oxidative stress and the interruption of nerve electrical signal conduction are …

Risks and benefits of clozapine and lithium co-prescribing: a systematic review and expert recommendations

H Verdoux, C Quiles, J de Leon - Schizophrenia research, 2023 - Elsevier
Objectives To identify the risks and benefits of clozapine‑lithium co-prescription. Methods
Articles published in English or French were identified with a MEDLINE, Web of Sciences …

Is lithium neuroprotective? An updated mechanistic illustrated review

F Ghanaatfar, A Ghanaatfar, P Isapour… - Fundamental & …, 2023 - Wiley Online Library
Neurodegeneration is a pathological process characterized by progressive neuronal
impairment, dysfunction, and loss due to mitochondrial dysfunction, oxidative stress …

[HTML][HTML] Excess resource use and costs of physical comorbidities in individuals with mental health disorders: A systematic literature review and meta-analysis

J Simon, D Wienand, AL Park, C Wippel… - European …, 2023 - Elsevier
Individuals with mental health disorders (MHDs) have worse physical health than the
general population, utilise healthcare resources more frequently and intensively, incurring …