Irinotecan-gut microbiota interactions and the capability of probiotics to mitigate Irinotecan-associated toxicity

MS Mahdy, AF Azmy, T Dishisha, WR Mohamed… - BMC microbiology, 2023 - Springer
Background Irinotecan is a chemotherapeutic agent used to treat a variety of tumors,
including colorectal cancer (CRC). In the intestine, it is transformed into SN-38 by gut …

NF-κB as a Potential Target for the Treatment and Prevention of Mucositis

P Abeesh, C Guruvayoorappan - Current Pharmaceutical …, 2023 - ingentaconnect.com
Mucositis is a debilitating and severe side effect of chemotherapy and radiotherapy. It is
responsible for reducing the patient's quality of life and represents a significant economic …

Effect of Green tea and black seed on methotrexate induced cytotoxicity of the oral mucosa, tongue and the submandibular salivary gland of Albino rats

R Fathi, D Abd Allah, I Helmy - Egyptian Dental Journal, 2023 - journals.ekb.eg
Background: Methotrexate (MTX) is a drug which has a wide application in the treatment of
malignant diseases and autoimmune diseases. The main side effect of MTX is oral mucositis …

Potential applications of hydroxy methyl cellulose mucoadhesive buccal patch containing zingibain for management of oral potentially malignant disorders

KP Das, AA Bajoria, S Patnaik, R Sahu - AIP Conference Proceedings, 2023 - pubs.aip.org
The Indian subcontinent has probably the most elevated pace of oral malignant growth on
the planet. 65% of all malignant growth in men and 33% of all diseases in ladies are tobacco …