Mast cell-mediated immune regulation in health and disease

KN Dileepan, VV Raveendran, R Sharma… - Frontiers in …, 2023 - frontiersin.org
Mast cells are important components of the immune system, and they perform pro-
inflammatory as well as anti-inflammatory roles in the complex process of immune regulation …

[HTML][HTML] COVID-19 and glomerular diseases

N Klomjit, L Zand, LD Cornell, MP Alexander - Kidney International Reports, 2023 - Elsevier
COVID-19 is a systemic disease, and the kidney is one of the target organs of infection.
Kidney injury is common and can occur in up to 40% of patients. Several glomerular …

SARS-CoV-2 spike protein induces endothelial inflammation via ACE2 independently of viral replication

AC Montezano, LL Camargo, S Mary, KB Neves… - Scientific Reports, 2023 - nature.com
Abstract COVID-19, caused by SARS-CoV-2, is a respiratory disease associated with
inflammation and endotheliitis. Mechanisms underling inflammatory processes are unclear …

[HTML][HTML] XBB. 1.5 Kraken cracked: Gibbs energies of binding and biosynthesis of the XBB. 1.5 variant of SARS-CoV-2

ME Popovic - Microbiological research, 2023 - Elsevier
Abstract The SARS-CoV-2 Hydra with many heads (variants) has been causing the COVID-
19 pandemic for 3 years. The appearance of every new head (SARS-CoV-2 variant) causes …

Never ending story? Evolution of SARS-CoV-2 monitored through Gibbs energies of biosynthesis and antigen-receptor binding of Omicron BQ. 1, BQ. 1.1, XBB and …

M Popovic - Microbial risk analysis, 2023 - Elsevier
RNA viruses exhibit a great tendency to mutate. Mutations occur in the parts of the genome
that encode the spike glycoprotein and less often in the rest of the genome. This is why …

Pathogenesis and mechanisms of SARS-CoV-2 infection in the intestine, liver, and pancreas

Z Khreefa, MT Barbier, AR Koksal, G Love, L Del Valle - Cells, 2023 - mdpi.com
The novel coronavirus, SARS-CoV-2, rapidly spread worldwide, causing an ongoing global
pandemic. While the respiratory system is the most common site of infection, a significant …

The SARS-CoV-2 Hydra, a tiny monster from the 21st century: Thermodynamics of the BA. 5.2 and BF. 7 variants

M Popovic - Microbial Risk Analysis, 2023 - Elsevier
SARS-CoV-2 resembles the ancient mythical creature Hydra. Just like with the Hydra, when
one head is cut, it is followed by appearance of two more heads, suppression of one SARS …

Efficacy of an unmodified bivalent mRNA vaccine against SARS-CoV-2 variants in female small animal models

B Corleis, D Hoffmann, S Rauch, C Fricke… - Nature …, 2023 - nature.com
Combining optimized spike (S) protein-encoding mRNA vaccines to target multiple SARS-
CoV-2 variants could improve control of the COVID-19 pandemic. We compare monovalent …

Interrelationship between COVID-19 and coagulopathy: pathophysiological and clinical evidence

B Ragnoli, B Da Re, A Galantino, S Kette… - International Journal of …, 2023 - mdpi.com
Since the first description of COVID-19 infection, among clinical manifestations of the
disease, including fever, dyspnea, cough, and fatigue, it was observed a high incidence of …

COVID-19 Biogenesis and Intracellular Transport

AA Mironov, MA Savin, GV Beznoussenko - International journal of …, 2023 - mdpi.com
SARS-CoV-2 is responsible for the COVID-19 pandemic. The structure of SARS-CoV-2 and
most of its proteins of have been deciphered. SARS-CoV-2 enters cells through the …