[HTML][HTML] The physiological functions and therapeutic potential of exosomes during the development and treatment of polycystic ovary syndrome
Z Zhang, C Shi, Z Wang - Frontiers in Physiology, 2023 - frontiersin.org
Polycystic ovary syndrome is a very common disease of gynecological endocrine,
accompanied by irregular menstruation, hyperandrogenism, metabolic abnormalities …
accompanied by irregular menstruation, hyperandrogenism, metabolic abnormalities …
Higher live birth rate following transdermal testosterone pretreatment in poor responders: a systematic review and meta-analysis
A systematic review and meta-analysis was performed aiming to identify good-quality
randomized controlled trials (RCT) evaluating testosterone pretreatment in poor responders …
randomized controlled trials (RCT) evaluating testosterone pretreatment in poor responders …
Dysregulation of steroid metabolome in follicular fluid links phthalate exposure to diminished ovarian reserve of childbearing-age women
Y Li, N Xiao, M Liu, Y Liu, A He, L Wang, H Luo… - Environmental …, 2023 - Elsevier
The widespread use of phthalates (PAEs) has drawn increasing attention due to their
endocrine disruption and reproductive toxicity, while the steroid metabolome is essential for …
endocrine disruption and reproductive toxicity, while the steroid metabolome is essential for …
Paxillin knockout in mouse granulosa cells increases fecundity
K Vann, AE Weidner, AC Walczyk… - Biology of …, 2023 - academic.oup.com
Paxillin is an intracellular adaptor protein involved in focal adhesions, cell response to
stress, steroid signaling, and apoptosis in reproductive tissues. To investigate the role of …
stress, steroid signaling, and apoptosis in reproductive tissues. To investigate the role of …
[HTML][HTML] Chlorogenic acid restores ovarian functions in mice with letrozole-induced polycystic ovarian syndrome via modulation of adiponectin receptor
Around the world, polycystic ovary syndrome (PCOS) is a complex endocrine-metabolic
condition that typically affects 6–20% of females. Our study's major goal was to examine how …
condition that typically affects 6–20% of females. Our study's major goal was to examine how …
[HTML][HTML] Androgen-induced exosomal miR-379-5p release determines granulosa cell fate: cellular mechanism involved in polycystic ovaries
R Salehi, BA Wyse, M Asare-Werehene… - Journal of Ovarian …, 2023 - Springer
Polycystic ovarian syndrome (PCOS) is a complex multi-factorial syndrome associated with
androgen excess and anovulatory infertility. In the current study, we investigated the role of …
androgen excess and anovulatory infertility. In the current study, we investigated the role of …
LncRNA MEG3 regulates ASK1/JNK axis-mediated apoptosis and autophagy via sponging miR-23a in granulosa cells of yak tertiary follicles
X Han, Y Pan, J Fan, M Wang, L Wang, J Wang… - Cellular …, 2023 - Elsevier
Apoptosis and autophagy in granulosa cells (GCs) are highly related to follicular
development and atresia. It has also been reported that they are related to LncRNA MEG3 …
development and atresia. It has also been reported that they are related to LncRNA MEG3 …
Eight weeks of androgen priming by daily low-dose hCG injections before ICSI treatment in women with low ovarian reserve
N Friis Wang, JW Bogstad, SE Pors… - Human …, 2023 - academic.oup.com
STUDY QUESTION Does 8 weeks of continuous low-dose hCG administration increase the
proportion of antral follicles that reach the preovulatory state during ovarian stimulation (OS) …
proportion of antral follicles that reach the preovulatory state during ovarian stimulation (OS) …
MicroRNA-27a-3p targeting Vangl1 and Vangl2 inhibits cell proliferation in mouse granulosa cells
H Tao, J Yang, M Xu, Z Liu, Y Liu, Q Xiong - Biochimica et Biophysica Acta …, 2023 - Elsevier
Background Mammalian folliculogenesis is the complex process through which primordial
follicles develop into preovulatory follicles. The chief function of ovarian follicle granulosa …
follicles develop into preovulatory follicles. The chief function of ovarian follicle granulosa …
Role of diacerein on steroidogenesis and folliculogenesis related genes in ovary of letrozole-induced PCOS mice
MZ ul haq Shah, VK Shrivastava, MA Mir… - Chemico-Biological …, 2023 - Elsevier
Polycystic ovary syndrome (PCOS), an intricate and multifaceted metabolic-endocrine
disorder that typically affects 6–20% of women of reproductive age and accounts for 70 …
disorder that typically affects 6–20% of women of reproductive age and accounts for 70 …