SMARCA4, also known as transcription activator, is an ATP-dependent catalytic subunit of
SWI/SNF (SWItch/Sucrose NonFermentable) chromatin-remodeling complexes that …

The dysregulation of the cell cycle is one of the hallmarks of cancer. Cyclin-dependent
kinase 4 (CDK4) and CDK6 play crucial roles in regulating cell cycle and other cellular …

Deficiency of SMARCA4, a member of the SWI/SNF chromatin remodeling complex, has
been described in a subset of undifferentiated gastroesophageal carcinomas with an …

Primary liver cancer (PLC) poses a leading threat to human health, and its treatment options
are limited. Meanwhile, the investigation of homogeneity and heterogeneity among PLCs …

The classification of poorly differentiated sinonasal carcinomas and their nonepithelial
mimics has experienced tremendous developments during the last 2 decades. These recent …

Purpose To improve the understanding of special types of tumors, we summarized and
analyzed the clinicopathological features and prognostic factors of SMARCA4‐deficient non …

Abstract SMARCA4 (BRG1) and SMARCA2 (BRM) are the two paralogous ATPases of the
SWI/SNF chromatin remodeling complexes frequently inactivated in cancers. Cells deficient …

Epigenetics refers to the study of genetic changes that can affect gene expression without
altering the underlying DNA sequence, including DNA methylation, histone modification …

Background RNA‐binding protein Quaking‐5 (QKI‐5), a major isoform of QKIs, inhibits tumor
progression in non‐small cell lung cancer (NSCLC). However, the underlying molecular …

Background Neuroblastoma (NB) is the most common extracranial malignancy in childhood;
however, the mechanisms underlying its aggressive characteristics still remain elusive …