Fatty acids are not only widely known as energy sources, but also play important roles in
many metabolic pathways. The significance of fatty acids in modulating the reproductive …

Background The human endometrium undergoes recurring cycles of growth, differentiation,
and breakdown in response to sex hormones. Dysregulation of epithelial-stromal …

Uterine glands and, by inference, their secretions impact uterine receptivity, blastocyst
implantation, stromal cell decidualization, and placental development. Changes in gland …

Postnatal development of the uterus involves specification of undifferentiated epithelium into
uterine-type epithelium. That specification is regulated by stromal-epithelial interactions as …

Implantation is the process by which a competent blastocyst burrows into the receptive
uterus to support embryo development. Successful implantation is of the utmost importance …

Estrogens play important roles in uterine growth and homeostasis through estrogen
receptors (ESR1 and ESR2). To address the role of ESR1-mediated tissue events in the …

Approximately 50% of pregnancies in humans fail, mostly before or during implantation. One
factor contributing to pregnancy loss is abnormal glucose metabolism in the endometrium …

Development of the mammary gland requires both proper hormone signaling and cross talk
between the stroma and epithelium. While estrogen receptor (ERα) expression in the …

In brief The regulation of AKT in the endometrium during many cellular processes such as
apoptosis and cell survival is crucial during the estrous cycle to ensure fertility. This research …