[HTML][HTML] The link between mitochondrial dysfunction and sarcopenia: an update focusing on the role of pyruvate dehydrogenase kinase 4
Sarcopenia, defined as a progressive loss of muscle mass and function, is typified by
mitochondrial dysfunction and loss of mitochondrial resilience. Sarcopenia is associated not …
mitochondrial dysfunction and loss of mitochondrial resilience. Sarcopenia is associated not …
Synthetic ERRα/β/γ agonist induces an ERRα-dependent acute aerobic exercise response and enhances exercise capacity
C Billon, S Sitaula, S Banerjee, R Welch… - ACS Chemical …, 2023 - ACS Publications
Repetitive physical exercise induces physiological adaptations in skeletal muscle that
improves exercise performance and is effective for the prevention and treatment of several …
improves exercise performance and is effective for the prevention and treatment of several …
ERRα fosters running endurance by driving myofiber aerobic transformation and fuel efficiency
H Xia, C Scholtes, CR Dufour, C Guluzian… - Molecular Metabolism, 2023 - Elsevier
Objective Estrogen related receptor α (ERRα) occupies a central node in the transcriptional
control of energy metabolism, including in skeletal muscle, but whether modulation of its …
control of energy metabolism, including in skeletal muscle, but whether modulation of its …
[HTML][HTML] Innately expressed estrogen-related receptors in the skeletal muscle are indispensable for exercise fitness
Transcriptional determinants in the skeletal muscle that govern exercise capacity, while
poorly defined, could provide molecular insights into how exercise improves fitness. Here …
poorly defined, could provide molecular insights into how exercise improves fitness. Here …
Association of Macronutrients Intake with Body Composition and Sarcopenic Obesity in Children and Adolescents: A Population-Based Analysis of the National Health …
B Yang, C Tang, Z Shi, L Gao - Nutrients, 2023 - mdpi.com
The association of macronutrients intake with body composition and sarcopenic obesity
remains uncertain in children and adolescents. We aimed to explore the association …
remains uncertain in children and adolescents. We aimed to explore the association …
Acute exercise in a hot environment increases heat shock protein 70 and peroxisome proliferator-activated receptor γ coactivator 1α mRNA in Thoroughbred horse …
Y Ebisuda, K Mukai, Y Takahashi, T Yoshida… - Frontiers in Veterinary …, 2023 - frontiersin.org
Heat acclimatization or acclimation training in horses is practiced to reduce physiological
strain and improve exercise performance in the heat, which can involve metabolic …
strain and improve exercise performance in the heat, which can involve metabolic …
MicroRNA-mediated reprogramming of glucose, fatty acid and amino acid metabolism in cancer
J Ding, Y Wen, X Yuan, X He - Genome Instability & Disease, 2023 - Springer
Cancer cells possess a unique metabolic phenotype, rewiring their metabolic pathways to
support energy-intensive and biosynthetic requirements for exuberant proliferation and …
support energy-intensive and biosynthetic requirements for exuberant proliferation and …
Development and pharmacological evaluation of a new chemical series of potent pan-ERR agonists, identification of SLU-PP-915
CS Hampton, S Sitaula, C Billon, K Haynes… - European Journal of …, 2023 - Elsevier
Estrogen-related receptors (ERR) are an orphan nuclear receptor sub-family that play a
critical role in regulating gene transcription for several physiological processes including …
critical role in regulating gene transcription for several physiological processes including …
Adriamycin downregulates the expression of KLF4 in cardiomyocytes in vitro and contributes to impaired cardiac energy metabolism in Adriamycin-induced …
Adriamycin is a well-known anthracycline chemotherapeutic agent widely used in treating a
variety of malignancies. However, Adriamycin's clinical use is limited due to its adverse side …
variety of malignancies. However, Adriamycin's clinical use is limited due to its adverse side …
CcpA-Knockout Staphylococcus aureus Induces Abnormal Metabolic Phenotype via the Activation of Hepatic STAT5/PDK4 Signaling in Diabetic Mice
Y Li, J Cai, Y Liu, C Li, X Chen, WL Wong, W Jiang… - Pathogens, 2023 - mdpi.com
Catabolite control protein A (CcpA), an important global regulatory protein, is extensively
found in S. aureus. Many studies have reported that CcpA plays a pivotal role in regulating …
found in S. aureus. Many studies have reported that CcpA plays a pivotal role in regulating …