Molecular stratification of arrhythmogenic mechanisms in the Andersen Tawil syndrome
AI Moreno-Manuel, LK Gutiérrez… - Cardiovascular …, 2023 - academic.oup.com
Andersen-Tawil syndrome (ATS) is a rare inheritable disease associated with loss-of-
function mutations in KCNJ2, the gene coding the strong inward rectifier potassium channel …
function mutations in KCNJ2, the gene coding the strong inward rectifier potassium channel …
The roles of connexins and gap junctions in the progression of cancer
M Zhou, M Zheng, X Zhou, S Tian, X Yang… - Cell Communication and …, 2023 - Springer
Gap junctions (GJs), which are composed of connexins (Cxs), provide channels for direct
information exchange between cells. Cx expression has a strong spatial specificity; …
information exchange between cells. Cx expression has a strong spatial specificity; …
[HTML][HTML] The Sar1 GTPase is dispensable for COPII-dependent cargo export from the ER
W Kasberg, P Luong, MG Hanna, K Minushkin, A Tsao… - Cell reports, 2023 - cell.com
Coat protein complex II (COPII) plays an integral role in the packaging of secretory cargoes
within membrane-enclosed transport carriers that leave the endoplasmic reticulum (ER) from …
within membrane-enclosed transport carriers that leave the endoplasmic reticulum (ER) from …
Nutrient deprivation alters the rate of COPII subunit recruitment at ER subdomains to tune secretory protein transport
W Kasberg, P Luong, KA Swift, A Audhya - Nature Communications, 2023 - nature.com
Co-assembly of the multilayered coat protein complex II (COPII) with the Sar1 GTPase at
subdomains of the endoplasmic reticulum (ER) enables secretory cargoes to be …
subdomains of the endoplasmic reticulum (ER) enables secretory cargoes to be …
Deficiency of Perry syndrome-associated p150Glued in midbrain dopaminergic neurons leads to progressive neurodegeneration and endoplasmic reticulum …
Multiple missense mutations in p150Glued are linked to Perry syndrome (PS), a rare
neurodegenerative disease pathologically characterized by loss of nigral dopaminergic …
neurodegenerative disease pathologically characterized by loss of nigral dopaminergic …
Endoplasmic reticulum exit sites are segregated for secretion based on cargo size
Summary TANGO1, TANGO1-Short, and cTAGE5 form stable complexes at the endoplasmic
reticulum exit sites (ERES) to preferably export bulky cargoes. Their C-terminal proline-rich …
reticulum exit sites (ERES) to preferably export bulky cargoes. Their C-terminal proline-rich …
The Early Secretory Pathway in Immunity
S Kim - 2023 - deepblue.lib.umich.edu
A central problem faced by T cells is the need to meet the demands of changing landscapes
in health and disease while adapting to rapid intracellular changes in gene expression and …
in health and disease while adapting to rapid intracellular changes in gene expression and …